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Atomistry » Zinc » PDB 1rrm-1sdy » 1s63 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 1rrm-1sdy » 1s63 » |
Zinc in PDB 1s63: Human Protein Farnesyltransferase Complexed with L-778,123 and FppEnzymatic activity of Human Protein Farnesyltransferase Complexed with L-778,123 and Fpp
All present enzymatic activity of Human Protein Farnesyltransferase Complexed with L-778,123 and Fpp:
2.5.1.58; 2.5.1.59; Protein crystallography data
The structure of Human Protein Farnesyltransferase Complexed with L-778,123 and Fpp, PDB code: 1s63
was solved by
S.B.Long,
P.J.Casey,
L.S.Beese,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1s63:
The structure of Human Protein Farnesyltransferase Complexed with L-778,123 and Fpp also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Human Protein Farnesyltransferase Complexed with L-778,123 and Fpp
(pdb code 1s63). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Human Protein Farnesyltransferase Complexed with L-778,123 and Fpp, PDB code: 1s63: Zinc binding site 1 out of 1 in 1s63Go back to![]() ![]()
Zinc binding site 1 out
of 1 in the Human Protein Farnesyltransferase Complexed with L-778,123 and Fpp
![]() Mono view ![]() Stereo pair view
Reference:
T.S.Reid,
S.B.Long,
L.S.Beese.
Crystallographic Analysis Reveals That Anticancer Clinical Candidate L-778,123 Inhibits Protein Farnesyltransferase and Geranylgeranyltransferase-I By Different Binding Modes. Biochemistry V. 43 9000 2004.
Page generated: Wed Oct 16 18:44:26 2024
ISSN: ISSN 0006-2960 PubMed: 15248757 DOI: 10.1021/BI049280B |
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