Zinc in PDB 1q09: Crystal Structure of the Zn(II) Form of E. Coli Zntr, A Zinc-Sensing Transcriptional Regulator (Space Group I4122)

The structure of Crystal Structure of the Zn(II) Form of E. Coli Zntr, A Zinc-Sensing Transcriptional Regulator (Space Group I4122), PDB code: 1q09 was solved by A.Changela, K.Chen, Y.Xue, J.Holschen, C.E.Outten, T.V.O'halloran, A.Mondragon, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	26.77 / 2.50
Space group	I 41 2 2
Cell size a, b, c (Å), α, β, γ (°)	83.799, 83.799, 179.993, 90.00, 90.00, 90.00
R / Rfree (%)	25.5 / 27.8

The binding sites of Zinc atom in the Crystal Structure of the Zn(II) Form of E. Coli Zntr, A Zinc-Sensing Transcriptional Regulator (Space Group I4122) (pdb code 1q09). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of the Zn(II) Form of E. Coli Zntr, A Zinc-Sensing Transcriptional Regulator (Space Group I4122), PDB code: 1q09:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of the Zn(II) Form of E. Coli Zntr, A Zinc-Sensing Transcriptional Regulator (Space Group I4122)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Zn(II) Form of E. Coli Zntr, A Zinc-Sensing Transcriptional Regulator (Space Group I4122) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:31.8 occ:1.00 O1 A:SO4302 2.3 32.7 1.0 SG A:CYS114 2.4 33.3 1.0 SG A:CYS124 2.4 27.9 1.0 CB A:CYS114 3.2 30.0 1.0 S A:SO4302 3.2 35.3 1.0 CB A:CYS124 3.4 28.5 1.0 O2 A:SO4302 3.4 32.6 1.0 CA A:CYS124 3.5 28.8 1.0 O4 A:SO4302 3.6 35.1 1.0 ZN A:ZN402 3.6 29.2 1.0 CA A:CYS114 3.8 31.6 1.0 N A:SER125 3.9 27.9 1.0 C A:CYS124 4.2 27.6 1.0 N A:CYS115 4.3 28.8 1.0 C A:CYS114 4.4 31.5 1.0 OG A:SER125 4.4 31.0 1.0 O3 A:SO4302 4.6 33.9 1.0 CD1 A:ILE126 4.6 27.8 1.0 CG1 A:ILE126 4.6 28.9 1.0 N A:CYS124 4.6 29.0 1.0 N A:ILE126 4.7 29.0 1.0 N A:GLY116 4.9 27.0 1.0 CA A:SER125 5.0 29.5 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of the Zn(II) Form of E. Coli Zntr, A Zinc-Sensing Transcriptional Regulator (Space Group I4122)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the Zn(II) Form of E. Coli Zntr, A Zinc-Sensing Transcriptional Regulator (Space Group I4122) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn402 b:29.2 occ:1.00 O2 A:SO4302 2.2 32.6 1.0 SG A:CYS115 2.4 27.2 1.0 ND1 A:HIS119 2.4 29.0 1.0 O4 A:SO4302 2.8 35.1 1.0 S A:SO4302 3.0 35.3 1.0 CG A:HIS119 3.2 29.7 1.0 CB A:HIS119 3.2 30.3 1.0 CB A:CYS115 3.4 28.2 1.0 CE1 A:HIS119 3.5 28.8 1.0 ZN A:ZN401 3.6 31.8 1.0 N A:CYS115 3.8 28.8 1.0 O1 A:SO4302 3.8 32.7 1.0 CA A:CYS115 4.1 28.2 1.0 O3 A:SO4302 4.2 33.9 1.0 CD2 A:HIS119 4.4 31.5 1.0 N A:GLY116 4.5 27.0 1.0 NE2 A:HIS119 4.6 30.7 1.0 SG A:CYS114 4.6 33.3 1.0 CA A:HIS119 4.6 31.5 1.0 C A:CYS115 4.7 26.9 1.0 O A:HIS119 4.8 32.1 1.0 C A:CYS114 4.9 31.5 1.0 OG1 A:THR117 4.9 31.3 1.0 C A:HIS119 5.0 31.8 1.0

A.Changela, K.Chen, Y.Xue, J.Holschen, C.E.Outten, T.V.O'halloran, A.Mondragon. Molecular Basis of Metal-Ion Selectivity and Zeptomolar Sensitivity By Cuer Science V. 301 1383 2003.
ISSN: ISSN 0036-8075
PubMed: 12958362
DOI: 10.1126/SCIENCE.1085950