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Atomistry » Zinc » PDB 1pvw-1q65 » 1pwp » |
Zinc in PDB 1pwp: Crystal Structure of the Anthrax Lethal Factor Complexed with Small Molecule Inhibitor Nsc 12155Enzymatic activity of Crystal Structure of the Anthrax Lethal Factor Complexed with Small Molecule Inhibitor Nsc 12155
All present enzymatic activity of Crystal Structure of the Anthrax Lethal Factor Complexed with Small Molecule Inhibitor Nsc 12155:
3.4.24.83; Protein crystallography data
The structure of Crystal Structure of the Anthrax Lethal Factor Complexed with Small Molecule Inhibitor Nsc 12155, PDB code: 1pwp
was solved by
T.Y.Wong,
R.Schwarzenbacher,
R.C.Liddington,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of the Anthrax Lethal Factor Complexed with Small Molecule Inhibitor Nsc 12155
(pdb code 1pwp). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of the Anthrax Lethal Factor Complexed with Small Molecule Inhibitor Nsc 12155, PDB code: 1pwp: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 1pwpGo back to![]() ![]()
Zinc binding site 1 out
of 2 in the Crystal Structure of the Anthrax Lethal Factor Complexed with Small Molecule Inhibitor Nsc 12155
![]() Mono view ![]() Stereo pair view
Zinc binding site 2 out of 2 in 1pwpGo back to![]() ![]()
Zinc binding site 2 out
of 2 in the Crystal Structure of the Anthrax Lethal Factor Complexed with Small Molecule Inhibitor Nsc 12155
![]() Mono view ![]() Stereo pair view
Reference:
R.G.Panchal,
A.R.Hermone,
T.L.Nguyen,
T.Y.Wong,
R.Schwarzenbacher,
J.Schmidt,
D.Lane,
C.Mcgrath,
B.E.Turk,
J.Burnett,
M.J.Aman,
S.Little,
E.A.Sausville,
D.W.Zaharevitz,
L.C.Cantley,
R.C.Liddington,
R.Gussio,
S.Bavari.
Identification of Small Molecule Inhibitors of Anthrax Lethal Factor. Nat.Struct.Mol.Biol. V. 11 67 2004.
Page generated: Wed Oct 16 17:56:59 2024
ISSN: ISSN 1545-9993 PubMed: 14718925 DOI: 10.1038/NSMB711 |
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