Atomistry » Zinc » PDB 1ndz-1nve » 1ndz
Atomistry »
  Zinc »
    PDB 1ndz-1nve »
      1ndz »

Zinc in PDB 1ndz: Crystal Structure of Adenosine Deaminase Complexed with FR235999

Enzymatic activity of Crystal Structure of Adenosine Deaminase Complexed with FR235999

All present enzymatic activity of Crystal Structure of Adenosine Deaminase Complexed with FR235999:
3.5.4.4;

Protein crystallography data

The structure of Crystal Structure of Adenosine Deaminase Complexed with FR235999, PDB code: 1ndz was solved by T.Kinoshita, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 8.00 / 2.00
Space group P 43 21 2
Cell size a, b, c (Å), α, β, γ (°) 78.060, 78.060, 136.710, 90.00, 90.00, 90.00
R / Rfree (%) n/a / n/a

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of Adenosine Deaminase Complexed with FR235999 (pdb code 1ndz). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Adenosine Deaminase Complexed with FR235999, PDB code: 1ndz:

Zinc binding site 1 out of 1 in 1ndz

Go back to Zinc Binding Sites List in 1ndz
Zinc binding site 1 out of 1 in the Crystal Structure of Adenosine Deaminase Complexed with FR235999


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Adenosine Deaminase Complexed with FR235999 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn400

b:16.9
occ:1.00
NE2 A:HIS17 1.9 12.3 1.0
O A:HOH1181 1.9 19.8 1.0
NE2 A:HIS15 2.0 16.5 1.0
NE2 A:HIS214 2.2 14.6 1.0
OD2 A:ASP295 2.3 22.5 1.0
CD2 A:HIS17 2.9 15.4 1.0
CE1 A:HIS15 3.0 15.8 1.0
CD2 A:HIS214 3.0 14.0 1.0
CD2 A:HIS15 3.1 16.1 1.0
CE1 A:HIS17 3.2 11.3 1.0
CE1 A:HIS214 3.2 12.2 1.0
CG A:ASP295 3.3 22.4 1.0
OD1 A:ASP295 3.7 22.6 1.0
NE2 A:HIS238 4.0 14.7 1.0
ND1 A:HIS15 4.2 16.1 1.0
N10 A:FR51001 4.2 19.8 1.0
CG A:HIS17 4.2 14.4 1.0
CG A:HIS15 4.2 16.1 1.0
CG A:HIS214 4.2 13.1 1.0
O A:HOH1009 4.3 30.4 1.0
ND1 A:HIS214 4.3 12.5 1.0
ND1 A:HIS17 4.4 15.2 1.0
C8 A:FR51001 4.4 18.0 1.0
CB A:ASP295 4.7 18.9 1.0
CD A:ARG101 4.7 13.1 1.0
O A:HOH1094 4.7 15.1 1.0
CD2 A:HIS238 4.8 14.4 1.0
O9 A:FR51001 4.9 19.9 1.0
O A:HOH1389 4.9 81.6 1.0
C5 A:FR51001 4.9 17.1 1.0
OD2 A:ASP296 5.0 19.8 1.0

Reference:

T.Terasaka, T.Kinoshita, M.Kuno, I.Nakanishi. A Highly Potent Non-Nucleoside Adenosine Deaminase Inhibitor: Efficient Drug Discovery By Intentional Lead Hybridization J.Am.Chem.Soc. V. 126 34 2004.
ISSN: ISSN 0002-7863
PubMed: 14709046
DOI: 10.1021/JA038606L
Page generated: Wed Oct 16 17:15:23 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy