Zinc in PDB 1mqj: Crystal Structure of the GLUR2 Ligand Binding Core (S1S2J) in Complex with Willardiine at 1.65 Angstroms Resolution

The structure of Crystal Structure of the GLUR2 Ligand Binding Core (S1S2J) in Complex with Willardiine at 1.65 Angstroms Resolution, PDB code: 1mqj was solved by R.Jin, T.G.Banke, M.L.Mayer, S.F.Traynelis, E.Gouaux, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.78 / 1.65
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	64.142, 93.223, 48.537, 90.00, 90.00, 90.00
R / Rfree (%)	20.8 / 22.9

The binding sites of Zinc atom in the Crystal Structure of the GLUR2 Ligand Binding Core (S1S2J) in Complex with Willardiine at 1.65 Angstroms Resolution (pdb code 1mqj). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the GLUR2 Ligand Binding Core (S1S2J) in Complex with Willardiine at 1.65 Angstroms Resolution, PDB code: 1mqj:

Zinc binding site 1 out of 1 in the Crystal Structure of the GLUR2 Ligand Binding Core (S1S2J) in Complex with Willardiine at 1.65 Angstroms Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the GLUR2 Ligand Binding Core (S1S2J) in Complex with Willardiine at 1.65 Angstroms Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:37.6 occ:1.00 NE2 A:HIS46 2.3 21.0 1.0 O A:HOH510 2.3 40.5 1.0 OE1 A:GLU42 2.4 20.2 1.0 CE1 A:HIS46 3.1 22.5 1.0 CD2 A:HIS46 3.3 20.4 1.0 CD A:GLU42 3.4 20.5 1.0 OE2 A:GLU42 3.7 27.7 1.0 NE2 A:GLN244 4.2 33.5 1.0 ND1 A:HIS46 4.3 21.9 1.0 CG A:HIS46 4.4 18.5 1.0 CD2 A:LEU241 4.4 12.9 1.0 O A:HOH639 4.7 55.6 1.0 CG A:GLU42 4.7 16.9 1.0

R.Jin, T.G.Banke, M.L.Mayer, S.F.Traynelis, E.Gouaux. Structural Basis For Partial Agonist Action at Ionotropic Glutamate Receptors Nat.Neurosci. V. 6 803 2003.
ISSN: ISSN 1097-6256
PubMed: 12872125
DOI: 10.1038/NN1091