Zinc in PDB 1im5: Crystal Structure of Pyrazinamidase of Pyrococcus Horikoshii in Complex with Zinc

All present enzymatic activity of Crystal Structure of Pyrazinamidase of Pyrococcus Horikoshii in Complex with Zinc:
3.5.1.19;

The structure of Crystal Structure of Pyrazinamidase of Pyrococcus Horikoshii in Complex with Zinc, PDB code: 1im5 was solved by X.Du, S.-H.Kim, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.65
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	32.978, 43.266, 55.553, 90.00, 101.34, 90.00
R / Rfree (%)	15.3 / 23.2

The binding sites of Zinc atom in the Crystal Structure of Pyrazinamidase of Pyrococcus Horikoshii in Complex with Zinc (pdb code 1im5). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Pyrazinamidase of Pyrococcus Horikoshii in Complex with Zinc, PDB code: 1im5:

Zinc binding site 1 out of 1 in the Crystal Structure of Pyrazinamidase of Pyrococcus Horikoshii in Complex with Zinc


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Pyrazinamidase of Pyrococcus Horikoshii in Complex with Zinc within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn400 b:13.4 occ:1.00 OD2 A:ASP52 2.0 16.0 1.0 NE2 A:HIS54 2.1 14.9 1.0 O A:HOH203 2.1 14.7 1.0 NE2 A:HIS71 2.2 9.9 1.0 O A:HOH214 2.2 21.4 1.0 O A:HOH223 2.4 19.8 1.0 CG A:ASP52 2.9 12.1 1.0 CE1 A:HIS54 3.0 13.6 1.0 CE1 A:HIS71 3.1 11.9 1.0 CD2 A:HIS54 3.2 13.1 1.0 CD2 A:HIS71 3.2 10.6 1.0 OD1 A:ASP52 3.4 16.3 1.0 ND1 A:HIS54 4.1 13.1 1.0 CB A:ASP52 4.2 13.9 1.0 OE2 A:GLU101 4.2 22.1 1.0 ND1 A:HIS71 4.2 12.4 1.0 CG A:HIS54 4.2 11.3 1.0 CG A:HIS71 4.3 12.4 1.0 OE1 A:GLU101 4.3 19.6 1.0 OG A:SER60 4.4 13.9 1.0 CZ A:PHE15 4.7 14.2 1.0 CD A:GLU101 4.7 22.4 1.0

X.Du, W.Wang, R.Kim, H.Yakota, H.Nguyen, S.H.Kim. Crystal Structure and Mechanism of Catalysis of A Pyrazinamidase From Pyrococcus Horikoshii. Biochemistry V. 40 14166 2001.
ISSN: ISSN 0006-2960
PubMed: 11714269
DOI: 10.1021/BI0115479