Zinc in PDB 1hxr: Crystal Structure of MSS4 at 1.65 Angstroms

The structure of Crystal Structure of MSS4 at 1.65 Angstroms, PDB code: 1hxr was solved by Z.Zhu, J.J.Dumas, S.E.Lietzke, D.G.Lambright, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	7.00 / 1.65
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	40.890, 49.870, 50.680, 90.00, 93.93, 90.00
R / Rfree (%)	21.4 / 25.6

The binding sites of Zinc atom in the Crystal Structure of MSS4 at 1.65 Angstroms (pdb code 1hxr). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of MSS4 at 1.65 Angstroms, PDB code: 1hxr:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of MSS4 at 1.65 Angstroms


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of MSS4 at 1.65 Angstroms within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn200 b:13.5 occ:1.00 SG A:CYS97 2.2 11.9 1.0 SG A:CYS26 2.3 13.6 1.0 SG A:CYS94 2.3 11.3 1.0 SG A:CYS23 2.4 11.4 1.0 CB A:CYS94 3.1 7.2 1.0 CB A:CYS97 3.1 13.6 1.0 CB A:CYS23 3.2 7.8 1.0 CB A:CYS26 3.4 10.8 1.0 N A:CYS97 3.6 11.8 1.0 N A:CYS26 3.7 12.2 1.0 CA A:CYS97 3.9 12.0 1.0 CA A:CYS26 4.1 12.6 1.0 CB A:SER28 4.2 13.9 1.0 O A:HOH304 4.4 12.3 1.0 CB A:ARG25 4.5 13.5 1.0 CA A:CYS94 4.6 10.2 1.0 C A:ARG25 4.6 13.5 1.0 C A:CYS97 4.7 10.7 1.0 CA A:CYS23 4.7 10.4 1.0 O A:HOH466 4.7 29.7 1.0 C A:ASP96 4.7 15.3 1.0 C A:CYS26 4.7 12.1 1.0 N A:SER28 4.8 12.6 1.0 N A:GLU98 4.8 10.0 1.0 N A:GLY27 4.8 11.9 1.0 CB A:ASP96 4.8 16.1 1.0 CA A:ARG25 4.9 13.4 1.0 N A:ARG25 5.0 13.8 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of MSS4 at 1.65 Angstroms


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of MSS4 at 1.65 Angstroms within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn201 b:12.2 occ:1.00 SG B:CYS97 2.3 11.1 1.0 SG B:CYS26 2.3 10.2 1.0 SG B:CYS94 2.3 12.9 1.0 SG B:CYS23 2.3 9.7 1.0 CB B:CYS94 3.1 11.8 1.0 CB B:CYS23 3.2 10.1 1.0 CB B:CYS97 3.3 11.3 1.0 CB B:CYS26 3.4 7.1 1.0 N B:CYS97 3.6 14.2 1.0 N B:CYS26 3.7 9.2 1.0 CA B:CYS97 4.0 10.3 1.0 CA B:CYS26 4.1 8.0 1.0 CB B:SER28 4.3 10.4 1.0 CB B:ARG25 4.4 11.4 1.0 O B:HOH308 4.4 10.4 1.0 CA B:CYS94 4.6 10.2 1.0 C B:ARG25 4.6 9.1 1.0 C B:ASP96 4.7 14.1 1.0 CA B:CYS23 4.7 11.2 1.0 C B:CYS26 4.7 8.5 1.0 C B:CYS97 4.7 11.9 1.0 N B:GLY27 4.8 7.8 1.0 N B:SER28 4.8 9.1 1.0 N B:GLU98 4.8 11.5 1.0 CB B:ASP96 4.8 16.3 1.0 CA B:ARG25 4.9 9.8 1.0

Z.Zhu, J.J.Dumas, S.E.Lietzke, D.G.Lambright. A Helical Turn Motif in MSS4 Is A Critical Determinant of Rab Binding and Nucleotide Release. Biochemistry V. 40 3027 2001.
ISSN: ISSN 0006-2960
PubMed: 11258916
DOI: 10.1021/BI002680O