Zinc in PDB 1g73: Crystal Structure of Smac Bound to Xiap-BIR3 Domain

The structure of Crystal Structure of Smac Bound to Xiap-BIR3 Domain, PDB code: 1g73 was solved by G.Wu, J.Chai, T.L.Suber, J.-W.Wu, Y.Shi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.00
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	48.100, 52.900, 67.100, 100.00, 104.10, 94.00
R / Rfree (%)	22.7 / 26.8

The binding sites of Zinc atom in the Crystal Structure of Smac Bound to Xiap-BIR3 Domain (pdb code 1g73). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Smac Bound to Xiap-BIR3 Domain, PDB code: 1g73:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Smac Bound to Xiap-BIR3 Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Smac Bound to Xiap-BIR3 Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn501 b:26.6 occ:1.00 CE1 C:HIS320 1.9 42.5 1.0 NE2 C:HIS320 2.0 47.1 1.0 SG C:CYS327 2.4 23.4 1.0 SG C:CYS303 2.4 20.7 1.0 SG C:CYS300 2.6 19.4 1.0 CB C:CYS327 2.9 19.8 1.0 CB C:CYS300 3.1 17.4 1.0 ND1 C:HIS320 3.2 27.7 1.0 CB C:CYS303 3.2 19.3 1.0 CD2 C:HIS320 3.3 40.9 1.0 N C:CYS303 3.7 21.6 1.0 CG C:HIS320 3.9 31.6 1.0 CA C:CYS303 4.0 21.9 1.0 CA C:CYS327 4.3 22.4 1.0 CA C:CYS300 4.6 16.6 1.0 CB C:HIS302 4.6 20.4 1.0 C C:HIS302 4.8 24.4 1.0 C C:CYS303 4.9 23.7 1.0 CB C:TYR324 4.9 28.2 1.0 CB C:TYR329 4.9 19.4 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Smac Bound to Xiap-BIR3 Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Smac Bound to Xiap-BIR3 Domain within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn502 b:30.1 occ:1.00 NE2 D:HIS320 2.1 33.1 1.0 SG D:CYS303 2.3 25.7 1.0 SG D:CYS327 2.3 29.7 1.0 SG D:CYS300 2.5 21.7 1.0 CD2 D:HIS320 3.0 25.0 1.0 CB D:CYS327 3.0 29.9 1.0 CB D:CYS303 3.1 24.7 1.0 CB D:CYS300 3.2 16.5 1.0 CE1 D:HIS320 3.2 26.5 1.0 N D:CYS303 3.6 22.3 1.0 CA D:CYS303 3.9 23.6 1.0 CG D:HIS320 4.2 26.1 1.0 ND1 D:HIS320 4.2 30.2 1.0 CA D:CYS327 4.4 30.8 1.0 CA D:CYS300 4.7 21.5 1.0 CB D:HIS302 4.7 26.1 1.0 C D:HIS302 4.8 18.9 1.0 C D:CYS303 4.8 23.6 1.0 N D:GLY304 4.8 22.4 1.0 CB D:TYR324 4.8 25.3 1.0

G.Wu, J.Chai, T.L.Suber, J.W.Wu, C.Du, X.Wang, Y.Shi. Structural Basis of Iap Recognition By Smac/Diablo. Nature V. 408 1008 2000.
ISSN: ISSN 0028-0836
PubMed: 11140638
DOI: 10.1038/35050012