Atomistry » Zinc » PDB 1cp6-1d4u » 1cqr
Atomistry »
  Zinc »
    PDB 1cp6-1d4u »
      1cqr »

Zinc in PDB 1cqr: Crystal Structure of the Stromelysin Catalytic Domain at 2.0 A Resolution

Enzymatic activity of Crystal Structure of the Stromelysin Catalytic Domain at 2.0 A Resolution

All present enzymatic activity of Crystal Structure of the Stromelysin Catalytic Domain at 2.0 A Resolution:
3.4.24.17;

Protein crystallography data

The structure of Crystal Structure of the Stromelysin Catalytic Domain at 2.0 A Resolution, PDB code: 1cqr was solved by L.Chen, T.J.Rydel, F.Gu, C.M.Dunaway, S.Pikul, K.M.Dunham, B.L.Barnett, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 12.00 / 2.00
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 38.200, 79.100, 107.400, 90.00, 90.00, 90.00
R / Rfree (%) 19.9 / 26.6

Other elements in 1cqr:

The structure of Crystal Structure of the Stromelysin Catalytic Domain at 2.0 A Resolution also contains other interesting chemical elements:

Calcium (Ca) 6 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of the Stromelysin Catalytic Domain at 2.0 A Resolution (pdb code 1cqr). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Crystal Structure of the Stromelysin Catalytic Domain at 2.0 A Resolution, PDB code: 1cqr:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in 1cqr

Go back to Zinc Binding Sites List in 1cqr
Zinc binding site 1 out of 4 in the Crystal Structure of the Stromelysin Catalytic Domain at 2.0 A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Stromelysin Catalytic Domain at 2.0 A Resolution within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1301

b:12.6
occ:1.00
 NE2 A:HIS201 2.1 9.6 1.0
NE2 A:HIS211 2.2 16.5 1.0
NE2 A:HIS205 2.2 7.2 1.0
CD2 A:HIS201 3.0 9.8 1.0
CE1 A:HIS211 3.0 18.7 1.0
CD2 A:HIS205 3.1 6.1 1.0
CD2 A:HIS211 3.1 16.8 1.0
CE1 A:HIS205 3.1 4.4 1.0
CE1 A:HIS201 3.2 8.9 1.0
ND1 A:HIS211 4.1 19.1 1.0
CG A:HIS201 4.2 8.9 1.0
O A:HOH14 4.2 24.7 1.0
CG A:HIS211 4.2 15.5 1.0
CG A:HIS205 4.3 5.5 1.0
ND1 A:HIS205 4.3 5.3 1.0
ND1 A:HIS201 4.3 7.3 1.0
O A:HOH15 4.6 23.2 1.0
CE A:MET219 4.8 3.5 1.0
OE2 A:GLU202 4.9 12.6 1.0

Zinc binding site 2 out of 4 in 1cqr

Go back to Zinc Binding Sites List in 1cqr
Zinc binding site 2 out of 4 in the Crystal Structure of the Stromelysin Catalytic Domain at 2.0 A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the Stromelysin Catalytic Domain at 2.0 A Resolution within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1302

b:12.4
occ:1.00
 OD2 A:ASP153 2.1 14.5 1.0
NE2 A:HIS151 2.1 6.1 1.0
ND1 A:HIS179 2.1 9.6 1.0
NE2 A:HIS166 2.1 9.8 1.0
CD2 A:HIS151 2.9 6.6 1.0
CE1 A:HIS166 3.0 8.3 1.0
CG A:ASP153 3.0 13.9 1.0
CE1 A:HIS179 3.0 9.1 1.0
CE1 A:HIS151 3.1 5.6 1.0
CG A:HIS179 3.1 8.2 1.0
CD2 A:HIS166 3.1 8.8 1.0
OD1 A:ASP153 3.2 11.3 1.0
CB A:HIS179 3.5 6.5 1.0
CG A:HIS151 4.1 7.1 1.0
ND1 A:HIS166 4.1 8.5 1.0
NE2 A:HIS179 4.1 10.6 1.0
ND1 A:HIS151 4.1 8.0 1.0
CG A:HIS166 4.2 7.6 1.0
CD2 A:HIS179 4.3 8.7 1.0
O A:TYR155 4.3 15.9 1.0
CB A:ASP153 4.4 12.2 1.0
OH A:TYR168 4.4 12.0 1.0
CZ A:PHE157 4.5 7.3 1.0
CE1 A:TYR168 4.6 7.1 1.0
CE1 A:PHE157 4.7 5.1 1.0
CA A:HIS179 4.9 7.4 1.0

Zinc binding site 3 out of 4 in 1cqr

Go back to Zinc Binding Sites List in 1cqr
Zinc binding site 3 out of 4 in the Crystal Structure of the Stromelysin Catalytic Domain at 2.0 A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of the Stromelysin Catalytic Domain at 2.0 A Resolution within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn2301

b:21.4
occ:1.00
 O B:HOH61 2.0 23.6 1.0
NE2 B:HIS201 2.2 15.0 1.0
NE2 B:HIS205 2.2 15.6 1.0
NE2 B:HIS211 2.2 23.8 1.0
CD2 B:HIS201 2.9 15.3 1.0
CD2 B:HIS205 3.0 14.3 1.0
CE1 B:HIS211 3.1 22.9 1.0
CD2 B:HIS211 3.1 24.8 1.0
CE1 B:HIS201 3.2 13.6 1.0
CE1 B:HIS205 3.2 13.0 1.0
O B:HOH69 3.7 23.9 1.0
OE2 B:GLU202 4.1 14.9 1.0
CG B:HIS201 4.1 14.5 1.0
O B:HOH50 4.1 17.9 1.0
ND1 B:HIS211 4.2 25.6 1.0
CG B:HIS205 4.2 11.0 1.0
CG B:HIS211 4.2 21.6 1.0
ND1 B:HIS201 4.2 15.4 1.0
ND1 B:HIS205 4.3 9.3 1.0
O B:HOH79 4.3 33.4 1.0
OE1 B:GLU202 4.3 12.2 1.0
CD B:GLU202 4.6 11.9 1.0

Zinc binding site 4 out of 4 in 1cqr

Go back to Zinc Binding Sites List in 1cqr
Zinc binding site 4 out of 4 in the Crystal Structure of the Stromelysin Catalytic Domain at 2.0 A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Crystal Structure of the Stromelysin Catalytic Domain at 2.0 A Resolution within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn2302

b:15.9
occ:1.00
 OD2 B:ASP153 2.0 15.7 1.0
NE2 B:HIS166 2.1 8.0 1.0
ND1 B:HIS179 2.1 11.6 1.0
NE2 B:HIS151 2.1 7.7 1.0
CG B:ASP153 2.9 11.6 1.0
CE1 B:HIS166 2.9 8.4 1.0
CE1 B:HIS179 2.9 8.8 1.0
CD2 B:HIS151 3.0 5.2 1.0
OD1 B:ASP153 3.0 13.7 1.0
CE1 B:HIS151 3.1 9.0 1.0
CD2 B:HIS166 3.1 10.3 1.0
CG B:HIS179 3.2 7.7 1.0
CB B:HIS179 3.6 9.5 1.0
OH B:TYR168 3.9 14.1 1.0
ND1 B:HIS166 4.1 10.4 1.0
NE2 B:HIS179 4.1 10.6 1.0
CG B:HIS151 4.2 9.0 1.0
CG B:HIS166 4.2 8.8 1.0
CB B:ASP153 4.2 10.6 1.0
O B:TYR155 4.2 16.3 1.0
ND1 B:HIS151 4.2 8.7 1.0
CD2 B:HIS179 4.3 9.8 1.0
CE1 B:TYR168 4.5 16.1 1.0
CZ B:PHE157 4.6 9.7 1.0
CE1 B:PHE157 4.6 9.1 1.0
CZ B:TYR168 4.7 16.4 1.0
O B:HOH22 5.0 10.8 1.0

Reference:

L.Chen, T.J.Rydel, F.Gu, C.M.Dunaway, S.Pikul, K.M.Dunham, B.L.Barnett. Crystal Structure of the Stromelysin Catalytic Domain at 2.0 A Resolution: Inhibitor-Induced Conformational Changes. J.Mol.Biol. V. 293 545 1999.
ISSN: ISSN 0022-2836
PubMed: 10543949
DOI: 10.1006/JMBI.1999.3147
Page generated: Sat Oct 12 23:16:03 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy