Zinc in PDB 1cp7: Aminopeptidase From Streptomyces Griseus

The structure of Aminopeptidase From Streptomyces Griseus, PDB code: 1cp7 was solved by R.Gilboa, H.M.Greenblatt, M.Perach, A.Spungin-Bialik, U.Lessel, D.Schomburg, S.Blumberg, G.Shoham, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	32.00 / 1.58
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	61.750, 61.750, 146.150, 90.00, 90.00, 90.00
R / Rfree (%)	14.4 / 17.1

The structure of Aminopeptidase From Streptomyces Griseus also contains other interesting chemical elements:

Calcium

(Ca)

1 atom

The binding sites of Zinc atom in the Aminopeptidase From Streptomyces Griseus (pdb code 1cp7). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Aminopeptidase From Streptomyces Griseus, PDB code: 1cp7:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Aminopeptidase From Streptomyces Griseus


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Aminopeptidase From Streptomyces Griseus within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn901 b:11.4 occ:1.00 OD1 A:ASP160 2.0 11.1 1.0 OD1 A:ASP97 2.0 11.0 1.0 NE2 A:HIS85 2.0 8.6 1.0 O A:HOH505 2.2 22.6 1.0 OD2 A:ASP160 2.7 12.1 1.0 CG A:ASP160 2.7 12.3 1.0 CD2 A:HIS85 3.0 8.7 1.0 CE1 A:HIS85 3.0 9.9 1.0 CG A:ASP97 3.0 12.7 1.0 OD2 A:ASP97 3.5 11.8 1.0 ZN A:ZN902 3.6 13.0 1.0 O A:HOH506 3.8 41.8 1.0 CB A:ASN98 4.0 8.8 1.0 OE1 A:GLU131 4.0 13.5 1.0 OE2 A:GLU132 4.0 13.7 1.0 ND1 A:HIS85 4.1 8.9 1.0 CG A:HIS85 4.1 6.8 1.0 CB A:ASP160 4.2 10.0 1.0 CG A:MET161 4.2 11.2 1.0 CB A:ASP97 4.3 9.5 1.0 CD A:GLU131 4.4 14.2 1.0 OE2 A:GLU131 4.4 18.1 1.0 CG A:ASN98 4.6 8.9 1.0 CA A:ASP97 4.6 8.7 1.0 SD A:MET161 4.6 13.0 1.0 CA A:ASP160 4.8 9.3 1.0 C A:ASP97 4.8 10.4 1.0 CD A:GLU132 4.9 13.0 1.0 C A:ASP160 4.9 10.9 1.0 CA A:ASN98 4.9 8.3 1.0 N A:ASN98 4.9 9.3 1.0 ND2 A:ASN98 5.0 8.7 1.0

Zinc binding site 2 out of 2 in the Aminopeptidase From Streptomyces Griseus


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Aminopeptidase From Streptomyces Griseus within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn902 b:13.0 occ:1.00 OE2 A:GLU132 2.0 13.7 1.0 OD2 A:ASP97 2.0 11.8 1.0 NE2 A:HIS247 2.0 14.7 1.0 O A:HOH505 2.3 22.6 1.0 OE1 A:GLU132 2.6 14.5 1.0 CD A:GLU132 2.7 13.0 1.0 CG A:ASP97 3.0 12.7 1.0 CD2 A:HIS247 3.0 13.2 1.0 CE1 A:HIS247 3.0 17.1 1.0 O A:HOH506 3.4 41.8 1.0 OD1 A:ASP97 3.4 11.0 1.0 ZN A:ZN901 3.6 11.4 1.0 O A:HOH303 3.9 12.1 1.0 O A:HOH578 3.9 41.1 1.0 CG A:GLU132 4.1 12.9 1.0 ND1 A:HIS247 4.1 16.3 1.0 CG A:HIS247 4.1 14.3 1.0 CE1 A:TYR246 4.2 17.7 1.0 OE1 A:GLU131 4.2 13.5 1.0 CB A:ASP97 4.3 9.5 1.0 OH A:TYR246 4.4 21.6 1.0 CE1 A:HIS85 4.4 9.9 1.0 NE2 A:HIS85 4.5 8.6 1.0 CZ A:TYR246 4.7 20.0 1.0 CG1 A:VAL89 4.7 12.9 1.0

R.Gilboa, H.M.Greenblatt, M.Perach, A.Spungin-Bialik, U.Lessel, G.Wohlfahrt, D.Schomburg, S.Blumberg, G.Shoham. Interactions of Streptomyces Griseus Aminopeptidase with A Methionine Product Analogue: A Structural Study at 1.53 A Resolution. Acta Crystallogr.,Sect.D V. 56 551 2000.
ISSN: ISSN 0907-4449
PubMed: 10771423
DOI: 10.1107/S0907444900002420