Atomistry » Zinc » PDB 1caq-1co4 » 1cny
Atomistry »
  Zinc »
    PDB 1caq-1co4 »
      1cny »

Zinc in PDB 1cny: Secondary Interactions Significantly Removed From the Sulfonamide Binding Pocket of Carbonic Anhydrase II Influence Binding Constants

Enzymatic activity of Secondary Interactions Significantly Removed From the Sulfonamide Binding Pocket of Carbonic Anhydrase II Influence Binding Constants

All present enzymatic activity of Secondary Interactions Significantly Removed From the Sulfonamide Binding Pocket of Carbonic Anhydrase II Influence Binding Constants:
4.2.1.1;

Protein crystallography data

The structure of Secondary Interactions Significantly Removed From the Sulfonamide Binding Pocket of Carbonic Anhydrase II Influence Binding Constants, PDB code: 1cny was solved by P.A.Boriack, D.W.Christianson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) N/A / 2.30
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 42.700, 41.700, 73.000, 90.00, 104.60, 90.00
R / Rfree (%) n/a / n/a

Other elements in 1cny:

The structure of Secondary Interactions Significantly Removed From the Sulfonamide Binding Pocket of Carbonic Anhydrase II Influence Binding Constants also contains other interesting chemical elements:

Mercury (Hg) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Secondary Interactions Significantly Removed From the Sulfonamide Binding Pocket of Carbonic Anhydrase II Influence Binding Constants (pdb code 1cny). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Secondary Interactions Significantly Removed From the Sulfonamide Binding Pocket of Carbonic Anhydrase II Influence Binding Constants, PDB code: 1cny:

Zinc binding site 1 out of 1 in 1cny

Go back to Zinc Binding Sites List in 1cny
Zinc binding site 1 out of 1 in the Secondary Interactions Significantly Removed From the Sulfonamide Binding Pocket of Carbonic Anhydrase II Influence Binding Constants


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Secondary Interactions Significantly Removed From the Sulfonamide Binding Pocket of Carbonic Anhydrase II Influence Binding Constants within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn262

b:7.3
occ:1.00
 ND1 A:HIS119 1.9 4.9 1.0
NE2 A:HIS94 2.1 3.0 1.0
NE2 A:HIS96 2.3 2.4 1.0
N1 A:EG3555 2.3 10.6 1.0
CE1 A:HIS119 2.8 5.0 1.0
CD2 A:HIS94 2.9 3.2 1.0
CD2 A:HIS96 3.0 2.5 1.0
O2 A:EG3555 3.1 10.8 1.0
CG A:HIS119 3.1 5.2 1.0
S A:EG3555 3.2 10.6 1.0
CE1 A:HIS94 3.3 3.2 1.0
CE1 A:HIS96 3.4 2.5 1.0
CB A:HIS119 3.6 5.2 1.0
OG1 A:THR199 3.9 4.1 1.0
OE1 A:GLU106 3.9 5.4 1.0
NE2 A:HIS119 4.0 5.0 1.0
CG A:HIS94 4.1 3.4 1.0
CD2 A:HIS119 4.1 4.9 1.0
O1 A:EG3555 4.2 10.3 1.0
CG A:HIS96 4.2 2.8 1.0
C4 A:EG3555 4.3 11.0 1.0
ND1 A:HIS94 4.3 3.1 1.0
ND1 A:HIS96 4.4 3.0 1.0
CD A:GLU106 4.8 5.5 1.0
C3 A:EG3555 4.9 11.1 1.0
CA A:HIS119 5.0 5.3 1.0

Reference:

P.A.Boriack, D.W.Christianson, J.Kingery-Wood, G.M.Whitesides. Secondary Interactions Significantly Removed From the Sulfonamide Binding Pocket of Carbonic Anhydrase II Influence Inhibitor Binding Constants. J.Med.Chem. V. 38 2286 1995.
ISSN: ISSN 0022-2623
PubMed: 7608893
DOI: 10.1021/JM00013A004
Page generated: Sat Oct 12 23:14:03 2024

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy