Zinc in PDB 1ca1: Alpha-Toxin From Clostridium Perfringens

All present enzymatic activity of Alpha-Toxin From Clostridium Perfringens:
3.1.4.3;

The structure of Alpha-Toxin From Clostridium Perfringens, PDB code: 1ca1 was solved by C.E.Naylor, A.K.Basak, R.W.Titball, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	25.00 / 1.90
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	61.300, 177.300, 79.100, 90.00, 90.00, 90.00
R / Rfree (%)	20.8 / 25.4

The structure of Alpha-Toxin From Clostridium Perfringens also contains other interesting chemical elements:

Cadmium

(Cd)

12 atoms

The binding sites of Zinc atom in the Alpha-Toxin From Clostridium Perfringens (pdb code 1ca1). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Alpha-Toxin From Clostridium Perfringens, PDB code: 1ca1:

Zinc binding site 1 out of 1 in the Alpha-Toxin From Clostridium Perfringens


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Alpha-Toxin From Clostridium Perfringens within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn371 b:17.5 occ:1.00 O A:TRP1 2.2 20.1 1.0 OD1 A:ASP130 2.3 15.5 1.0 NE2 A:HIS11 2.4 17.5 1.0 O A:HOH573 2.7 32.9 1.0 N A:TRP1 2.7 23.4 1.0 C A:TRP1 3.1 20.9 1.0 CD2 A:HIS11 3.1 17.5 1.0 CA A:TRP1 3.3 19.9 1.0 CG A:ASP130 3.4 18.9 1.0 CD A:CD373 3.5 19.6 1.0 CE1 A:HIS11 3.5 19.9 1.0 OD2 A:ASP130 3.8 20.5 1.0 CB A:TRP1 3.9 18.8 1.0 CE1 A:HIS126 4.0 11.1 1.0 OD2 A:ASP56 4.1 20.8 1.0 O A:HOH572 4.2 38.1 1.0 NE2 A:HIS126 4.3 11.5 1.0 N A:ASP2 4.3 23.0 1.0 CG A:HIS11 4.3 17.8 1.0 ND1 A:HIS11 4.5 19.5 1.0 CG A:TRP1 4.5 20.4 1.0 CB A:ASP130 4.6 16.3 1.0 CD1 A:TRP1 4.6 22.8 1.0 OE2 A:GLU152 4.7 22.5 1.0 ND1 A:HIS126 4.8 10.0 1.0 CA A:ASP130 4.8 15.2 1.0 CD A:CD372 4.8 22.6 1.0 NE2 A:HIS136 4.9 19.4 1.0 CG A:ASP56 5.0 20.4 1.0 OD1 A:ASP56 5.0 16.5 1.0

C.E.Naylor, J.T.Eaton, A.Howells, N.Justin, D.S.Moss, R.W.Titball, A.K.Basak. Structure of the Key Toxin in Gas Gangrene. Nat.Struct.Biol. V. 5 738 1998.
ISSN: ISSN 1072-8368
PubMed: 9699639
DOI: 10.1038/1447