Zinc in PDB 8yrs: Crystal Structure of Human RECQ1 Helicase Containing A Flexible Linker in Complex with Tailed Duplex Dna

All present enzymatic activity of Crystal Structure of Human RECQ1 Helicase Containing A Flexible Linker in Complex with Tailed Duplex Dna:
3.6.4.12;

The structure of Crystal Structure of Human RECQ1 Helicase Containing A Flexible Linker in Complex with Tailed Duplex Dna, PDB code: 8yrs was solved by T.Das, A.K.Das, A.Ganguly, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.64 / 2.43
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	83.323, 96.573, 96.806, 90, 106.88, 90
R / Rfree (%)	23.8 / 25.7

The binding sites of Zinc atom in the Crystal Structure of Human RECQ1 Helicase Containing A Flexible Linker in Complex with Tailed Duplex Dna (pdb code 8yrs). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Human RECQ1 Helicase Containing A Flexible Linker in Complex with Tailed Duplex Dna, PDB code: 8yrs:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Human RECQ1 Helicase Containing A Flexible Linker in Complex with Tailed Duplex Dna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human RECQ1 Helicase Containing A Flexible Linker in Complex with Tailed Duplex Dna within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn900 b:55.5 occ:1.00 SG A:CYS471 2.3 51.0 1.0 SG A:CYS453 2.3 44.5 1.0 SG A:CYS478 2.3 61.2 1.0 SG A:CYS475 2.3 52.1 1.0 CB A:CYS471 2.9 56.8 1.0 CB A:CYS478 3.1 58.9 1.0 CB A:CYS453 3.2 44.8 1.0 CB A:CYS475 3.3 47.9 1.0 CA A:CYS453 3.8 42.0 1.0 N A:CYS475 3.9 53.4 1.0 CA A:CYS475 4.1 51.3 1.0 N A:ARG454 4.1 56.5 1.0 CA A:CYS478 4.2 59.1 1.0 N A:CYS478 4.2 55.5 1.0 CA A:CYS471 4.4 57.9 1.0 C A:CYS453 4.4 39.7 1.0 O A:CYS475 4.5 55.0 1.0 C A:CYS475 4.6 52.0 1.0 C A:MET474 4.7 52.2 1.0 N A:ARG455 4.8 43.9 1.0 N A:MET474 4.8 58.3 1.0 C A:CYS471 4.9 60.2 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Human RECQ1 Helicase Containing A Flexible Linker in Complex with Tailed Duplex Dna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Human RECQ1 Helicase Containing A Flexible Linker in Complex with Tailed Duplex Dna within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn900 b:146.3 occ:1.00 SG B:CYS453 2.3 48.1 1.0 SG B:CYS475 2.3 48.5 1.0 SG B:CYS471 2.3 57.4 1.0 SG B:CYS478 2.3 67.2 1.0 CB B:CYS471 3.0 56.7 1.0 CB B:CYS478 3.1 69.0 1.0 CB B:CYS453 3.1 45.5 1.0 CB B:CYS475 3.4 41.8 1.0 CA B:CYS453 3.8 45.4 1.0 N B:ARG454 4.1 32.7 1.0 N B:CYS475 4.1 50.4 1.0 CA B:CYS478 4.3 65.2 1.0 CA B:CYS475 4.3 47.2 1.0 N B:CYS478 4.3 61.0 1.0 C B:CYS453 4.4 44.1 1.0 CA B:CYS471 4.5 64.1 1.0 O B:CYS475 4.7 48.4 1.0 N B:ARG455 4.8 30.1 1.0 C B:CYS475 4.8 48.8 1.0 C B:MET474 4.8 36.9 1.0 C B:CYS471 5.0 61.8 1.0

T.Das, A.K.Das, A.Ganguly. Crystal Structure of Human RECQ1 Helicase Containing A Flexible Linker in Complex with Tailed Duplex Dna To Be Published.