Zinc in PDB 8twi: Cryo-Em Structure of the PP2A:B55-FAM122A Complex, PP2AC Body

All present enzymatic activity of Cryo-Em Structure of the PP2A:B55-FAM122A Complex, PP2AC Body:
3.1.3.16;

The structure of Cryo-Em Structure of the PP2A:B55-FAM122A Complex, PP2AC Body also contains other interesting chemical elements:

Iron

(Fe)

1 atom

The binding sites of Zinc atom in the Cryo-Em Structure of the PP2A:B55-FAM122A Complex, PP2AC Body (pdb code 8twi). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryo-Em Structure of the PP2A:B55-FAM122A Complex, PP2AC Body, PDB code: 8twi:

Zinc binding site 1 out of 1 in the Cryo-Em Structure of the PP2A:B55-FAM122A Complex, PP2AC Body


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of the PP2A:B55-FAM122A Complex, PP2AC Body within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn402 b:187.0 occ:1.00 OD2 C:ASP85 2.0 125.0 1.0 OD2 C:ASP57 2.2 117.0 1.0 NE2 C:HIS59 2.3 105.2 1.0 FE C:FE401 3.1 162.2 1.0 CG C:ASP85 3.2 114.9 1.0 CE1 C:HIS59 3.2 104.0 1.0 CG C:ASP57 3.3 110.3 1.0 HE1 C:HIS59 3.3 101.1 1.0 CD2 C:HIS59 3.3 101.8 1.0 HB3 C:ASP85 3.5 112.8 1.0 HD2 C:HIS59 3.5 100.9 1.0 HB3 C:ASP57 3.6 105.3 1.0 HA C:HIS241 3.6 108.5 1.0 HD2 C:HIS118 3.8 110.5 1.0 CB C:ASP85 3.8 111.3 1.0 HE1 C:PHE260 3.8 99.8 1.0 CB C:ASP57 3.9 100.2 1.0 HB2 C:ASP85 4.0 113.1 1.0 HE1 C:HIS167 4.0 103.1 1.0 HB2 C:ASP57 4.1 105.2 1.0 OD1 C:ASP85 4.2 112.8 1.0 CD2 C:HIS118 4.2 105.2 1.0 OD1 C:ASP57 4.2 109.5 1.0 ND1 C:HIS59 4.4 97.5 1.0 OH C:TYR265 4.4 119.3 1.0 HH C:TYR265 4.4 110.8 1.0 CG C:HIS59 4.4 93.7 1.0 NE2 C:HIS118 4.5 105.2 1.0 NE2 C:HIS167 4.5 101.3 1.0 CA C:HIS241 4.5 108.3 1.0 CE1 C:HIS167 4.6 107.0 1.0 OD1 C:ASN117 4.6 125.4 1.0 CE1 C:PHE260 4.6 99.5 1.0 ND1 C:HIS241 4.7 107.6 1.0 HZ C:PHE260 4.7 98.1 1.0 O C:HIS241 4.8 110.5 1.0 C C:HIS241 4.8 107.4 1.0 H C:HIS241 4.9 108.2 1.0

S.K.R.Padi, M.R.Vos, A.D.S.Santiago, R.J.Godek, J.R.Fuller, M.S.Kelker, R.Page, W.Peti. Cryo-Em Structure of PP2A:B55-FAM122A Reveals A Bipartite Mechanism of FAM122A-Mediated Inhibition and A Motif That Confers Binding Specificity to PP2A:B55 To Be Published.