Zinc in PDB 8trh: The Idrc Bound Human Core Mediator Complex

The binding sites of Zinc atom in the The Idrc Bound Human Core Mediator Complex (pdb code 8trh). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the The Idrc Bound Human Core Mediator Complex, PDB code: 8trh:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the The Idrc Bound Human Core Mediator Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The Idrc Bound Human Core Mediator Complex within 5.0Å range: probe atom residue distance (Å) B Occ 0:Zn401 b:29.9 occ:1.00 ND1 0:HIS306 2.1 19.6 1.0 SG 0:CYS284 2.3 31.5 1.0 SG 0:CYS281 2.3 24.3 1.0 SG 0:CYS309 2.3 26.6 1.0 CG 0:HIS306 2.8 19.6 1.0 CB 0:CYS281 2.9 24.3 1.0 CB 0:HIS306 3.0 19.6 1.0 CE1 0:HIS306 3.2 19.6 1.0 CB 0:CYS309 3.5 26.6 1.0 N 0:HIS306 3.6 19.6 1.0 CB 0:CYS284 3.7 31.5 1.0 CA 0:HIS306 3.9 19.6 1.0 N 0:CYS284 3.9 31.5 1.0 CD2 0:HIS306 4.0 19.6 1.0 NE2 0:HIS306 4.2 19.6 1.0 CA 0:CYS284 4.4 31.5 1.0 CA 0:CYS281 4.4 24.3 1.0 CG 0:GLN289 4.6 25.6 1.0 CB 0:ARG283 4.7 23.5 1.0 C 0:PHE305 4.8 26.2 1.0 CA 0:CYS309 4.9 26.6 1.0 N 0:ARG283 4.9 23.5 1.0 C 0:HIS306 4.9 19.6 1.0 C 0:ARG283 5.0 23.5 1.0

Zinc binding site 2 out of 2 in the The Idrc Bound Human Core Mediator Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of The Idrc Bound Human Core Mediator Complex within 5.0Å range: probe atom residue distance (Å) B Occ P:Zn901 b:20.7 occ:1.00 SG P:CYS798 2.3 29.1 1.0 SG P:CYS801 2.3 28.8 1.0 SG P:CYS827 2.3 41.1 1.0 CB P:CYS827 2.8 41.1 1.0 CB P:CYS798 3.2 29.1 1.0 CB P:CYS801 3.5 28.8 1.0 C P:CYS827 3.6 41.1 1.0 CA P:CYS827 3.8 41.1 1.0 O P:CYS827 3.8 41.1 1.0 C P:LEU828 3.8 19.9 1.0 N P:LEU828 3.9 19.9 1.0 SG P:CYS803 4.1 26.5 1.0 O P:LEU828 4.1 19.9 1.0 N P:CYS801 4.3 28.8 1.0 CA P:LEU828 4.5 19.9 1.0 CA P:CYS801 4.5 28.8 1.0 NH2 P:ARG800 4.6 25.8 1.0 N P:CYS827 4.6 41.1 1.0 CA P:CYS798 4.7 29.1 1.0 CZ P:ARG800 4.9 25.8 1.0

T.C.Chao, S.F.Chen, H.J.Kim, H.C.Tang, H.C.Tseng, A.Xu, L.Palao 3Rd, S.Khadka, T.Li, M.F.Huang, D.F.Lee, K.Murakami, T.G.Boyer, K.L.Tsai. Structural Basis of the Human Transcriptional Mediator Regulated By Its Dissociable Kinase Module. Mol.Cell 2024.
ISSN: ISSN 1097-2765
PubMed: 39321804
DOI: 10.1016/J.MOLCEL.2024.09.001