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Zinc in PDB 8so0: Cryo-Em Structure of the PP2A:B55-FAM122A Complex

Enzymatic activity of Cryo-Em Structure of the PP2A:B55-FAM122A Complex

All present enzymatic activity of Cryo-Em Structure of the PP2A:B55-FAM122A Complex:
3.1.3.16;

Other elements in 8so0:

The structure of Cryo-Em Structure of the PP2A:B55-FAM122A Complex also contains other interesting chemical elements:

Iron (Fe) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Cryo-Em Structure of the PP2A:B55-FAM122A Complex (pdb code 8so0). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryo-Em Structure of the PP2A:B55-FAM122A Complex, PDB code: 8so0:

Zinc binding site 1 out of 1 in 8so0

Go back to Zinc Binding Sites List in 8so0
Zinc binding site 1 out of 1 in the Cryo-Em Structure of the PP2A:B55-FAM122A Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of the PP2A:B55-FAM122A Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Zn402

b:135.8
occ:1.00
OD2 C:ASP85 2.1 81.7 1.0
OD2 C:ASP57 2.3 78.0 1.0
NE2 C:HIS59 2.3 67.8 1.0
FE C:FE401 2.9 113.8 1.0
CE1 C:HIS59 3.1 69.8 1.0
HE1 C:HIS59 3.2 64.5 1.0
CG C:ASP85 3.2 73.0 1.0
CG C:ASP57 3.4 71.8 1.0
CD2 C:HIS59 3.4 62.7 1.0
HA C:HIS241 3.5 72.4 1.0
HB3 C:ASP85 3.6 71.8 1.0
HB3 C:ASP57 3.6 65.2 1.0
HD2 C:HIS59 3.6 63.6 1.0
HD2 C:HIS118 3.8 76.5 1.0
CB C:ASP85 3.9 65.3 1.0
HE1 C:PHE260 3.9 65.4 1.0
HE1 C:HIS167 3.9 65.8 1.0
ND1 C:HIS241 4.0 76.6 1.0
CB C:ASP57 4.0 56.0 1.0
HB2 C:ASP85 4.0 72.8 1.0
HB2 C:ASP57 4.2 65.5 1.0
OD1 C:ASP85 4.2 83.3 1.0
CD2 C:HIS118 4.2 78.3 1.0
OD1 C:ASP57 4.3 74.1 1.0
ND1 C:HIS59 4.3 60.5 1.0
NE2 C:HIS118 4.4 78.7 1.0
CA C:HIS241 4.4 69.0 1.0
CG C:HIS59 4.5 57.6 1.0
OH C:TYR265 4.5 81.8 1.0
HE1 C:HIS241 4.5 74.8 1.0
O C:HIS241 4.5 79.1 1.0
OD1 C:ASN117 4.6 87.1 1.0
CE1 C:HIS167 4.6 64.8 1.0
NE2 C:HIS167 4.6 62.3 1.0
CE1 C:HIS241 4.6 80.0 1.0
HH C:TYR265 4.7 71.1 1.0
C C:HIS241 4.7 73.6 1.0
CE1 C:PHE260 4.7 66.1 1.0
HZ C:PHE260 4.8 63.7 1.0
HD22 C:ASN117 4.9 79.6 1.0
CG C:HIS241 5.0 68.0 1.0
HE1 C:TYR265 5.0 69.3 1.0

Reference:

S.K.R.Padi, M.R.Vos, A.D.S.Santiago, R.J.Godek, J.R.Fuller, M.S.Kelker, R.Page, W.Peti. Cryo-Em Structure of PP2A:B55-FAM122A Reveals A Bipartite Mechanism of FAM122A-Mediated Inhibition and A Motif That Confers Binding Specificity to PP2A:B55 To Be Published.
Page generated: Thu Dec 28 13:38:23 2023

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