Zinc in PDB 8snm: Structure of Mature Human ADAM17/IRHOM2 Sheddase Complex in Complex with ADAM17 Prodomain

All present enzymatic activity of Structure of Mature Human ADAM17/IRHOM2 Sheddase Complex in Complex with ADAM17 Prodomain:
3.4.24.86;

The structure of Structure of Mature Human ADAM17/IRHOM2 Sheddase Complex in Complex with ADAM17 Prodomain also contains other interesting chemical elements:

Calcium

(Ca)

1 atom

The binding sites of Zinc atom in the Structure of Mature Human ADAM17/IRHOM2 Sheddase Complex in Complex with ADAM17 Prodomain (pdb code 8snm). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of Mature Human ADAM17/IRHOM2 Sheddase Complex in Complex with ADAM17 Prodomain, PDB code: 8snm:

Zinc binding site 1 out of 1 in the Structure of Mature Human ADAM17/IRHOM2 Sheddase Complex in Complex with ADAM17 Prodomain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Mature Human ADAM17/IRHOM2 Sheddase Complex in Complex with ADAM17 Prodomain within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn901 b:85.5 occ:1.00 NE2 B:HIS415 2.0 78.9 1.0 NE2 B:HIS409 2.0 70.4 1.0 NE2 B:HIS405 2.1 65.8 1.0 SG A:CYS184 2.1 74.2 1.0 CD2 B:HIS405 2.6 65.8 1.0 CD2 B:HIS415 2.9 78.9 1.0 CE1 B:HIS409 2.9 70.4 1.0 CD2 B:HIS409 3.0 70.4 1.0 CE1 B:HIS415 3.1 78.9 1.0 CE1 B:HIS405 3.3 65.8 1.0 CB A:CYS184 3.5 74.2 1.0 CG B:HIS405 3.9 65.8 1.0 ND1 B:HIS409 4.0 70.4 1.0 CG B:HIS415 4.1 78.9 1.0 CG B:HIS409 4.1 70.4 1.0 ND1 B:HIS415 4.1 78.9 1.0 ND1 B:HIS405 4.2 65.8 1.0 N A:CYS184 4.4 74.2 1.0 OE2 B:GLU406 4.4 64.1 1.0 CB A:VAL183 4.5 73.3 1.0 CA A:CYS184 4.6 74.2 1.0 OH A:TYR186 4.9 81.8 1.0 CG1 A:VAL183 4.9 73.3 1.0 C A:VAL183 5.0 73.3 1.0

H.Zhao, Y.Dai, Y.Wang, C.H.Lee. Structure of Mature Human ADAM17/IRHOM2 Sheddase Complex in Complex with ADAM17 Prodomain To Be Published.