Zinc in PDB 8sn2: Cryo-Em Structure of the Human Nucleosome Core Particle in Complex with RNF168 and UBCH5C (UBCH5C Chemically Conjugated to Histone H2A)

All present enzymatic activity of Cryo-Em Structure of the Human Nucleosome Core Particle in Complex with RNF168 and UBCH5C (UBCH5C Chemically Conjugated to Histone H2A):
2.3.2.23; 2.3.2.24; 2.3.2.27;

The binding sites of Zinc atom in the Cryo-Em Structure of the Human Nucleosome Core Particle in Complex with RNF168 and UBCH5C (UBCH5C Chemically Conjugated to Histone H2A) (pdb code 8sn2). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryo-Em Structure of the Human Nucleosome Core Particle in Complex with RNF168 and UBCH5C (UBCH5C Chemically Conjugated to Histone H2A), PDB code: 8sn2:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Cryo-Em Structure of the Human Nucleosome Core Particle in Complex with RNF168 and UBCH5C (UBCH5C Chemically Conjugated to Histone H2A)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of the Human Nucleosome Core Particle in Complex with RNF168 and UBCH5C (UBCH5C Chemically Conjugated to Histone H2A) within 5.0Å range: probe atom residue distance (Å) B Occ K:Zn301 b:99.8 occ:1.00 ND1 K:HIS33 2.1 45.0 1.0 SG K:CYS31 2.3 43.0 1.0 SG K:CYS51 2.3 44.8 1.0 SG K:CYS54 2.3 44.6 1.0 CE1 K:HIS33 2.3 45.0 1.0 CG K:HIS33 2.9 45.0 1.0 NE2 K:HIS33 3.2 45.0 1.0 CB K:CYS54 3.2 44.6 1.0 CB K:CYS51 3.3 44.8 1.0 CB K:CYS31 3.3 43.0 1.0 CD2 K:HIS33 3.5 45.0 1.0 N K:CYS54 3.5 44.6 1.0 CB K:HIS33 3.8 45.0 1.0 CA K:CYS54 3.9 44.6 1.0 CB K:PHE53 4.2 43.4 1.0 O K:CYS31 4.5 43.0 1.0 C K:PHE53 4.6 43.4 1.0 CA K:CYS31 4.6 43.0 1.0 C K:CYS54 4.6 44.6 1.0 CA K:CYS51 4.7 44.8 1.0 C K:CYS31 4.8 43.0 1.0 N K:ARG55 4.8 37.7 1.0 CA K:PHE53 4.8 43.4 1.0 N K:PHE53 4.8 43.4 1.0 CD1 K:LEU29 4.9 39.4 1.0

Zinc binding site 2 out of 2 in the Cryo-Em Structure of the Human Nucleosome Core Particle in Complex with RNF168 and UBCH5C (UBCH5C Chemically Conjugated to Histone H2A)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of the Human Nucleosome Core Particle in Complex with RNF168 and UBCH5C (UBCH5C Chemically Conjugated to Histone H2A) within 5.0Å range: probe atom residue distance (Å) B Occ K:Zn302 b:82.0 occ:1.00 SG K:CYS39 2.3 43.1 1.0 SG K:CYS16 2.3 44.3 1.0 SG K:CYS36 2.3 45.6 1.0 SG K:CYS19 2.3 41.7 1.0 CB K:CYS16 3.4 44.3 1.0 CB K:CYS39 3.5 43.1 1.0 CB K:CYS19 3.6 41.7 1.0 CB K:CYS36 3.6 45.6 1.0 N K:CYS19 3.9 41.7 1.0 N K:CYS36 4.1 45.6 1.0 CA K:CYS36 4.3 45.6 1.0 CA K:CYS19 4.4 41.7 1.0 O K:CYS36 4.4 45.6 1.0 CB K:ILE18 4.5 43.8 1.0 N K:CYS39 4.6 43.1 1.0 C K:CYS36 4.7 45.6 1.0 CA K:CYS39 4.7 43.1 1.0 CA K:CYS16 4.7 44.3 1.0 O K:CYS16 4.7 44.3 1.0 C K:ILE18 4.9 43.8 1.0 C K:CYS16 4.9 44.3 1.0

Q.Hu, M.V.Botuyan, D.Zhao, G.Cui, G.Mer. Cryo-Em Structure of the Human Nucleosome Core Particle in Complex with RNF168 and UBCH5C (UBCH5C Chemically Conjugated to Histone H2A) To Be Published.