Zinc in PDB 8sl1: Cryo-Em Structure of Papp-A2

The structure of Cryo-Em Structure of Papp-A2 also contains other interesting chemical elements:

Calcium

(Ca)

2 atoms

The binding sites of Zinc atom in the Cryo-Em Structure of Papp-A2 (pdb code 8sl1). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryo-Em Structure of Papp-A2, PDB code: 8sl1:

Zinc binding site 1 out of 1 in the Cryo-Em Structure of Papp-A2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Papp-A2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1801 b:99.5 occ:1.00 NE2 A:HIS499 2.0 35.4 1.0 NE2 A:HIS509 2.0 48.6 1.0 NE2 A:HIS503 2.0 31.3 1.0 O A:HOH2301 2.4 49.7 1.0 CE1 A:HIS509 2.6 51.3 1.0 CD2 A:HIS503 2.6 35.5 1.0 CE1 A:HIS499 3.0 38.9 1.0 CD2 A:HIS499 3.0 35.6 1.0 CE1 A:HIS503 3.2 34.9 1.0 CD2 A:HIS509 3.3 45.2 1.0 ND1 A:HIS509 3.8 50.7 1.0 CG A:HIS503 3.9 30.7 1.0 ND1 A:HIS499 4.1 35.6 1.0 ND1 A:HIS503 4.1 35.2 1.0 CG A:HIS499 4.2 30.5 1.0 CG A:HIS509 4.2 44.9 1.0 CE1 A:TYR575 4.2 65.2 1.0 OH A:TYR575 4.4 62.9 1.0 NE2 A:GLN500 4.4 35.5 1.0 CZ A:TYR575 4.7 66.6 1.0 OE1 A:GLN500 4.9 31.6 1.0

J.Sridar, A.Mafi, R.A.Judge, J.Xu, K.A.Kong, J.C.K.Wang, V.S.Stoll, G.Koukos, R.J.Simon, D.Eaton, M.Bratkowski, Q.Hao. Cryo-Em Structure of Human Papp-A2 and Mechanism of Substrate Recognition Commun Chem V. 6 234 2023.
ISSN: ESSN 2399-3669
DOI: 10.1038/S42004-023-01032-Y