Zinc in PDB 8rgq: Open Complex I From Murine Liver

All present enzymatic activity of Open Complex I From Murine Liver:
7.1.1.2;

The structure of Open Complex I From Murine Liver also contains other interesting chemical elements:

Potassium	(K)	1 atom
Iron	(Fe)	28 atoms
Magnesium	(Mg)	1 atom

The binding sites of Zinc atom in the Open Complex I From Murine Liver (pdb code 8rgq). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Open Complex I From Murine Liver, PDB code: 8rgq:

Zinc binding site 1 out of 1 in the Open Complex I From Murine Liver


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Open Complex I From Murine Liver within 5.0Å range: probe atom residue distance (Å) B Occ 7:Zn201 b:86.0 occ:1.00 NE2 7:HIS68 2.0 90.2 1.0 SG 7:CYS87 2.3 90.4 1.0 SG 7:CYS84 2.3 72.4 1.0 SG 7:CYS59 2.3 82.6 1.0 CE1 7:HIS68 2.9 84.1 1.0 CD2 7:HIS68 3.0 73.8 1.0 CB 7:CYS84 3.3 66.0 1.0 CB 7:CYS87 3.3 66.7 1.0 CB 7:CYS59 3.3 70.5 1.0 N 7:GLY61 3.7 70.8 1.0 N 7:CYS87 3.9 68.6 1.0 CA 7:GLY61 4.0 79.6 1.0 ND1 7:HIS68 4.0 77.2 1.0 CG 7:HIS68 4.1 69.5 1.0 CA 7:CYS87 4.2 65.9 1.0 C 7:CYS59 4.3 74.2 1.0 CA 7:CYS59 4.4 71.0 1.0 C 7:ASP60 4.4 74.3 1.0 N 7:ASP60 4.4 72.0 1.0 O 7:CYS59 4.6 80.4 1.0 CB 7:TYR86 4.7 73.9 1.0 CA 7:CYS84 4.7 63.5 1.0 CA 7:ASP60 4.8 59.1 1.0 C 7:CYS87 5.0 64.8 1.0 C 7:TYR86 5.0 60.2 1.0

I.Vercellino, L.A.Sazanov. SCAF1 Drives the Compositional Diversity of Mammalian Respirasomes. Nat.Struct.Mol.Biol. 2024.
ISSN: ESSN 1545-9985
PubMed: 38575788
DOI: 10.1038/S41594-024-01255-0