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Zinc in PDB 8om1: Mitochondrial Complex I From Mus Musculus in the Active State

Enzymatic activity of Mitochondrial Complex I From Mus Musculus in the Active State

All present enzymatic activity of Mitochondrial Complex I From Mus Musculus in the Active State:
7.1.1.2;

Other elements in 8om1:

The structure of Mitochondrial Complex I From Mus Musculus in the Active State also contains other interesting chemical elements:

Iron (Fe) 28 atoms
Sodium (Na) 1 atom
Magnesium (Mg) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Mitochondrial Complex I From Mus Musculus in the Active State (pdb code 8om1). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Mitochondrial Complex I From Mus Musculus in the Active State, PDB code: 8om1:

Zinc binding site 1 out of 1 in 8om1

Go back to Zinc Binding Sites List in 8om1
Zinc binding site 1 out of 1 in the Mitochondrial Complex I From Mus Musculus in the Active State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Mitochondrial Complex I From Mus Musculus in the Active State within 5.0Å range:
probe atom residue distance (Å) B Occ
R:Zn201

b:29.1
occ:1.00
NE2 R:HIS68 2.0 14.3 1.0
SG R:CYS84 2.3 16.8 1.0
SG R:CYS59 2.3 16.6 1.0
SG R:CYS87 2.3 15.5 1.0
CE1 R:HIS68 2.9 14.3 1.0
CD2 R:HIS68 3.1 14.3 1.0
CB R:CYS84 3.3 16.8 1.0
CB R:CYS87 3.4 15.5 1.0
CB R:CYS59 3.4 16.6 1.0
N R:GLY61 3.7 16.2 1.0
N R:CYS87 3.7 15.5 1.0
CA R:GLY61 3.8 16.2 1.0
ND1 R:HIS68 4.0 14.3 1.0
CA R:CYS87 4.1 15.5 1.0
CG R:HIS68 4.1 14.3 1.0
C R:CYS59 4.3 16.6 1.0
CA R:CYS59 4.4 16.6 1.0
CB R:TYR86 4.5 13.6 1.0
O R:CYS59 4.5 16.6 1.0
C R:ASP60 4.5 16.2 1.0
N R:ASP60 4.6 16.2 1.0
CA R:CYS84 4.7 16.8 1.0
C R:TYR86 4.8 13.6 1.0
C R:CYS87 4.8 15.5 1.0
CA R:ASP60 4.9 16.2 1.0
O R:HOH337 4.9 16.2 1.0
N R:GLY88 4.9 16.6 1.0
N R:TYR86 5.0 13.6 1.0
CA R:TYR86 5.0 13.6 1.0

Reference:

D.N.Grba, I.Chung, H.R.Bridges, A.A.Agip, J.Hirst. Investigation of Hydrated Channels and Proton Pathways in A High-Resolution Cryo-Em Structure of Mammalian Complex I. Sci Adv V. 9 I1359 2023.
ISSN: ESSN 2375-2548
PubMed: 37531432
DOI: 10.1126/SCIADV.ADI1359
Page generated: Thu Dec 28 13:29:31 2023

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