Zinc in PDB 8f5o: Structure of Leishmania Tarentolae Ift-A (State 1)

The binding sites of Zinc atom in the Structure of Leishmania Tarentolae Ift-A (State 1) (pdb code 8f5o). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Structure of Leishmania Tarentolae Ift-A (State 1), PDB code: 8f5o:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Structure of Leishmania Tarentolae Ift-A (State 1)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Leishmania Tarentolae Ift-A (State 1) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn2000 b:495.8 occ:1.00 SG B:CYS1217 2.3 464.2 1.0 SG B:CYS1214 2.3 466.3 1.0 SG B:CYS1235 2.3 448.0 1.0 SG B:CYS1232 2.3 435.6 1.0 CB B:CYS1232 3.0 435.6 1.0 CB B:CYS1214 3.3 466.3 1.0 CB B:CYS1217 3.5 464.2 1.0 CB B:CYS1235 3.8 448.0 1.0 N B:CYS1235 3.9 448.0 1.0 N B:CYS1217 4.0 464.2 1.0 CA B:CYS1217 4.3 464.2 1.0 CA B:CYS1235 4.4 448.0 1.0 CH2 B:TRP1212 4.5 449.5 1.0 OG1 B:THR1237 4.5 436.0 1.0 CB B:LEU1234 4.5 435.9 1.0 CA B:CYS1232 4.5 435.6 1.0 CA B:CYS1214 4.8 466.3 1.0 N B:LEU1234 4.9 435.9 1.0 C B:LEU1234 5.0 435.9 1.0 N B:HIS1236 5.0 426.9 1.0

Zinc binding site 2 out of 4 in the Structure of Leishmania Tarentolae Ift-A (State 1)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of Leishmania Tarentolae Ift-A (State 1) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn2001 b:522.2 occ:1.00 SG B:CYS1188 2.3 421.4 1.0 SG B:CYS1177 2.3 448.9 1.0 SG B:CYS1191 2.3 441.8 1.0 SG B:CYS1174 2.3 437.6 1.0 CB B:CYS1188 3.1 421.4 1.0 CB B:CYS1174 3.1 437.6 1.0 CB B:CYS1191 3.2 441.8 1.0 OG B:SER1179 3.4 426.9 1.0 N B:CYS1191 3.6 441.8 1.0 CB B:CYS1177 3.8 448.9 1.0 CA B:CYS1191 3.9 441.8 1.0 N B:CYS1177 4.0 448.9 1.0 CA B:CYS1177 4.5 448.9 1.0 CA B:CYS1188 4.5 421.4 1.0 CB B:THR1176 4.6 439.4 1.0 CA B:CYS1174 4.6 437.6 1.0 C B:CYS1191 4.6 441.8 1.0 CB B:LYS1190 4.7 432.9 1.0 CB B:SER1179 4.7 426.9 1.0 C B:LYS1190 4.7 432.9 1.0 N B:GLN1192 4.7 427.0 1.0 N B:LYS1190 4.9 432.9 1.0 ND2 B:ASN1181 4.9 394.8 1.0 CZ B:PHE1195 5.0 411.9 1.0

Zinc binding site 3 out of 4 in the Structure of Leishmania Tarentolae Ift-A (State 1)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Structure of Leishmania Tarentolae Ift-A (State 1) within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn2000 b:278.3 occ:1.00 SG C:CYS1061 2.3 205.1 1.0 SG C:CYS1044 2.3 229.3 1.0 SG C:CYS1047 2.3 232.9 1.0 SG C:CYS1064 2.3 216.4 1.0 CB C:CYS1047 2.8 232.9 1.0 CB C:CYS1044 3.0 229.3 1.0 CB C:CYS1061 3.0 205.1 1.0 N C:CYS1047 3.6 232.9 1.0 CB C:CYS1064 3.7 216.4 1.0 N C:CYS1064 3.7 216.4 1.0 CA C:CYS1047 3.8 232.9 1.0 CA C:CYS1064 4.2 216.4 1.0 CB C:HIS1066 4.3 205.0 1.0 CA C:CYS1044 4.3 229.3 1.0 O C:CYS1044 4.4 229.3 1.0 CB C:ASN1063 4.4 211.2 1.0 CA C:CYS1061 4.5 205.1 1.0 C C:CYS1044 4.5 229.3 1.0 C C:CYS1064 4.7 216.4 1.0 N C:HIS1066 4.8 205.0 1.0 C C:ARG1046 4.8 226.5 1.0 C C:CYS1047 4.8 232.9 1.0 C C:ASN1063 4.8 211.2 1.0 CB C:ARG1046 4.8 226.5 1.0 N C:ASN1063 4.9 211.2 1.0 ND2 C:ASN1063 4.9 211.2 1.0 CA C:ASN1063 4.9 211.2 1.0 N C:PHE1065 5.0 202.9 1.0

Zinc binding site 4 out of 4 in the Structure of Leishmania Tarentolae Ift-A (State 1)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Structure of Leishmania Tarentolae Ift-A (State 1) within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn2001 b:172.1 occ:1.00 SG C:CYS1232 2.3 137.5 1.0 SG C:CYS1254 2.3 115.6 1.0 SG C:CYS1257 2.3 127.6 1.0 SG C:CYS1235 2.3 128.4 1.0 CB C:CYS1235 2.7 128.4 1.0 CB C:CYS1232 2.7 137.5 1.0 CB C:CYS1254 2.9 115.6 1.0 N C:CYS1235 3.7 128.4 1.0 CA C:CYS1235 3.8 128.4 1.0 CB C:CYS1257 3.9 127.6 1.0 CA C:CYS1232 4.1 137.5 1.0 OH C:TYR1244 4.2 126.6 1.0 O C:CYS1232 4.2 137.5 1.0 N C:CYS1257 4.3 127.6 1.0 C C:CYS1232 4.4 137.5 1.0 CA C:CYS1254 4.4 115.6 1.0 C C:GLY1234 4.5 132.8 1.0 CB C:TYR1259 4.5 133.6 1.0 CA C:CYS1257 4.6 127.6 1.0 CE1 C:PHE1239 4.7 134.9 1.0 C C:CYS1235 4.8 128.4 1.0 CE1 C:TYR1244 4.8 126.6 1.0 CZ C:TYR1244 4.8 126.6 1.0 N C:GLY1234 4.9 132.8 1.0 CA C:GLY1234 4.9 132.8 1.0 N C:CYS1232 5.0 137.5 1.0 CZ C:PHE1239 5.0 134.9 1.0

S.Meleppattu, H.Zhou, J.Dai, M.Gui, A.Brown. Mechanism of Ift-A Polymerization Into Trains For Ciliary Transport Cell(Cambridge,Mass.) 2022.
ISSN: ISSN 0092-8674
DOI: 10.1016/J.CELL.2022.11.033