Zinc in PDB 8f1k: Sign Rna Polymerase Early-Melted Intermediate Bound to Full Duplex Dna Fragment DHSU36 (-12T)

Enzymatic activity of Sign Rna Polymerase Early-Melted Intermediate Bound to Full Duplex Dna Fragment DHSU36 (-12T)

All present enzymatic activity of Sign Rna Polymerase Early-Melted Intermediate Bound to Full Duplex Dna Fragment DHSU36 (-12T):
2.7.7.6;

Other elements in 8f1k:

The structure of Sign Rna Polymerase Early-Melted Intermediate Bound to Full Duplex Dna Fragment DHSU36 (-12T) also contains other interesting chemical elements:

Magnesium (Mg) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Sign Rna Polymerase Early-Melted Intermediate Bound to Full Duplex Dna Fragment DHSU36 (-12T) (pdb code 8f1k). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Sign Rna Polymerase Early-Melted Intermediate Bound to Full Duplex Dna Fragment DHSU36 (-12T), PDB code: 8f1k:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 8f1k

Go back to Zinc Binding Sites List in 8f1k
Zinc binding site 1 out of 2 in the Sign Rna Polymerase Early-Melted Intermediate Bound to Full Duplex Dna Fragment DHSU36 (-12T)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Sign Rna Polymerase Early-Melted Intermediate Bound to Full Duplex Dna Fragment DHSU36 (-12T) within 5.0Å range:
probe atom residue distance (Å) B Occ
J:Zn1502

b:75.5
occ:1.00
SG J:CYS72 2.3 59.5 1.0
SG J:CYS85 2.3 61.2 1.0
SG J:CYS88 2.3 52.6 1.0
SG J:CYS70 2.3 45.6 1.0
CB J:CYS85 3.1 46.4 1.0
CB J:CYS70 3.1 39.4 1.0
CB J:CYS72 3.7 51.6 1.0
CB J:CYS88 3.7 44.6 1.0
N J:CYS72 3.8 52.0 1.0
N J:GLY73 4.0 54.9 1.0
N J:CYS88 4.1 46.8 1.0
CA J:CYS72 4.2 52.3 1.0
N J:LEU71 4.2 47.2 1.0
N J:LYS74 4.3 49.6 1.0
CA J:CYS70 4.3 39.4 1.0
C J:CYS70 4.4 41.6 1.0
CA J:CYS88 4.5 44.8 1.0
CA J:CYS85 4.5 45.1 1.0
CB J:LYS74 4.5 50.0 1.0
C J:CYS72 4.6 56.2 1.0
CG J:LYS74 4.8 54.7 1.0
CD2 J:TYR75 4.8 46.6 1.0
C J:LEU71 4.8 47.0 1.0
CB J:LYS87 4.9 55.2 1.0

Zinc binding site 2 out of 2 in 8f1k

Go back to Zinc Binding Sites List in 8f1k
Zinc binding site 2 out of 2 in the Sign Rna Polymerase Early-Melted Intermediate Bound to Full Duplex Dna Fragment DHSU36 (-12T)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Sign Rna Polymerase Early-Melted Intermediate Bound to Full Duplex Dna Fragment DHSU36 (-12T) within 5.0Å range:
probe atom residue distance (Å) B Occ
J:Zn1503

b:73.7
occ:1.00
SG J:CYS895 2.3 39.9 1.0
SG J:CYS898 2.3 46.8 1.0
SG J:CYS888 2.3 37.7 1.0
SG J:CYS814 2.3 43.6 1.0
CB J:CYS898 3.1 29.4 1.0
CB J:CYS888 3.5 36.6 1.0
CB J:CYS814 3.5 42.9 1.0
CB J:CYS895 3.7 28.0 1.0
NH2 J:ARG883 3.9 39.3 1.0
CA J:CYS888 3.9 35.6 1.0
N J:CYS898 4.2 24.6 1.0
CA J:CYS898 4.2 19.9 1.0
N J:CYS895 4.3 21.1 1.0
N J:CYS814 4.3 42.3 1.0
OG1 J:THR890 4.4 39.3 1.0
N J:ASP889 4.4 44.9 1.0
CG2 J:THR816 4.5 49.4 1.0
CA J:CYS895 4.6 22.5 1.0
CA J:CYS814 4.6 45.5 1.0
C J:CYS888 4.6 41.3 1.0
CZ J:ARG883 4.8 43.6 1.0
N J:THR890 5.0 42.6 1.0
O J:SER887 5.0 49.4 1.0

Reference:

A.U.Mueller, J.Chen, M.Wu, C.Chiu, B.T.Nixon, E.A.Campbell, S.A.Darst. A General Mechanism For Transcription Bubble Nucleation in Bacteria. Proc.Natl.Acad.Sci.Usa V. 120 74120 2023.
ISSN: ESSN 1091-6490
PubMed: 36972428
DOI: 10.1073/PNAS.2220874120
Page generated: Wed Oct 30 20:09:45 2024

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