Zinc in PDB 8eg7: Cryo-Em Structure of Pre-Consensus Elemental Paused Elongation Complex

Enzymatic activity of Cryo-Em Structure of Pre-Consensus Elemental Paused Elongation Complex

All present enzymatic activity of Cryo-Em Structure of Pre-Consensus Elemental Paused Elongation Complex:
2.7.7.6;

Other elements in 8eg7:

The structure of Cryo-Em Structure of Pre-Consensus Elemental Paused Elongation Complex also contains other interesting chemical elements:

Magnesium (Mg) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Cryo-Em Structure of Pre-Consensus Elemental Paused Elongation Complex (pdb code 8eg7). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryo-Em Structure of Pre-Consensus Elemental Paused Elongation Complex, PDB code: 8eg7:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 8eg7

Go back to Zinc Binding Sites List in 8eg7
Zinc binding site 1 out of 2 in the Cryo-Em Structure of Pre-Consensus Elemental Paused Elongation Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Pre-Consensus Elemental Paused Elongation Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
J:Zn1502

b:163.2
occ:1.00
SG J:CYS70 2.3 87.0 1.0
SG J:CYS88 2.3 87.2 1.0
SG J:CYS85 2.3 89.7 1.0
SG J:CYS72 2.3 88.8 1.0
CB J:CYS85 3.0 89.7 1.0
CB J:CYS72 3.7 88.8 1.0
N J:CYS72 3.8 88.8 1.0
CB J:CYS70 3.9 87.0 1.0
CB J:CYS88 3.9 87.2 1.0
N J:CYS88 4.0 87.2 1.0
CA J:CYS72 4.3 88.8 1.0
N J:LEU71 4.3 80.2 1.0
CA J:CYS85 4.4 89.7 1.0
CA J:CYS88 4.5 87.2 1.0
CB J:LYS87 4.6 90.3 1.0
N J:GLY89 4.7 78.9 1.0
N J:LYS87 4.8 90.3 1.0
C J:LEU71 4.8 80.2 1.0
CB J:LYS74 4.9 87.2 1.0
C J:LYS87 4.9 90.3 1.0
CA J:LEU71 4.9 80.2 1.0
CA J:CYS70 5.0 87.0 1.0
N J:GLY73 5.0 87.3 1.0
C J:CYS70 5.0 87.0 1.0
C J:CYS85 5.0 89.7 1.0
C J:CYS72 5.0 88.8 1.0

Zinc binding site 2 out of 2 in 8eg7

Go back to Zinc Binding Sites List in 8eg7
Zinc binding site 2 out of 2 in the Cryo-Em Structure of Pre-Consensus Elemental Paused Elongation Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of Pre-Consensus Elemental Paused Elongation Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
J:Zn1503

b:58.5
occ:1.00
SG J:CYS895 2.3 35.3 1.0
SG J:CYS898 2.3 37.1 1.0
SG J:CYS814 2.3 45.0 1.0
SG J:CYS888 2.3 39.2 1.0
CB J:CYS898 3.0 37.1 1.0
CB J:CYS814 3.0 45.0 1.0
CB J:CYS888 3.3 39.2 1.0
CB J:CYS895 3.5 35.3 1.0
CA J:CYS888 3.8 39.2 1.0
NH2 J:ARG883 3.9 41.5 1.0
N J:CYS814 4.1 45.0 1.0
CA J:CYS898 4.1 37.1 1.0
N J:CYS898 4.2 37.1 1.0
CA J:CYS814 4.2 45.0 1.0
N J:CYS895 4.2 35.3 1.0
OG1 J:THR890 4.4 43.0 1.0
CA J:CYS895 4.4 35.3 1.0
N J:ASP889 4.5 46.6 1.0
OG1 J:THR816 4.6 48.3 1.0
C J:CYS888 4.6 39.2 1.0
O J:CYS895 4.8 35.3 1.0
CZ J:ARG883 4.9 41.5 1.0
C J:CYS895 4.9 35.3 1.0
N J:CYS888 5.0 39.2 1.0

Reference:

J.Y.Kang, T.V.Mishanina, Y.Bao, J.Chen, E.Llewellyn, J.Liu, S.A.Darst, R.Landick. An Ensemble of Interconverting Conformations of the Elemental Paused Transcription Complex Creates Regulatory Options. Proc.Natl.Acad.Sci.Usa V. 120 45120 2023.
ISSN: ESSN 1091-6490
PubMed: 36795753
DOI: 10.1073/PNAS.2215945120
Page generated: Sat Apr 8 08:36:57 2023

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy