Zinc in PDB 8dgt: Cryo-Em Structure of A Ras/Raf Complex (State 2)

All present enzymatic activity of Cryo-Em Structure of A Ras/Raf Complex (State 2):
2.7.11.1; 2.7.12.2;

The structure of Cryo-Em Structure of A Ras/Raf Complex (State 2) also contains other interesting chemical elements:

Iodine	(I)	1 atom
Fluorine	(F)	1 atom
Magnesium	(Mg)	2 atoms

The binding sites of Zinc atom in the Cryo-Em Structure of A Ras/Raf Complex (State 2) (pdb code 8dgt). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryo-Em Structure of A Ras/Raf Complex (State 2), PDB code: 8dgt:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Cryo-Em Structure of A Ras/Raf Complex (State 2)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of A Ras/Raf Complex (State 2) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn802 b:111.7 occ:1.00 ND1 A:HIS269 2.1 94.1 1.0 SG A:CYS272 2.4 91.0 1.0 SG A:CYS248 2.4 92.2 1.0 SG A:CYS251 2.5 91.2 1.0 CE1 A:HIS269 3.0 94.1 1.0 CG A:HIS269 3.0 94.1 1.0 CB A:CYS272 3.3 91.0 1.0 CB A:CYS248 3.3 92.2 1.0 CB A:HIS269 3.4 94.1 1.0 CB A:CYS251 3.4 91.2 1.0 N A:HIS269 3.6 94.1 1.0 CA A:HIS269 4.1 94.1 1.0 NE2 A:HIS269 4.1 94.1 1.0 CD2 A:HIS269 4.2 94.1 1.0 N A:CYS251 4.2 91.2 1.0 CA A:CYS251 4.4 91.2 1.0 NE A:ARG271 4.6 92.1 1.0 CA A:CYS272 4.7 91.0 1.0 CD2 A:PHE250 4.7 88.4 1.0 C A:PHE268 4.7 94.2 1.0 CA A:CYS248 4.8 92.2 1.0 CA A:PHE268 4.8 94.2 1.0 CG A:ARG271 4.8 92.1 1.0 N A:CYS272 4.8 91.0 1.0 C A:HIS269 5.0 94.1 1.0

Zinc binding site 2 out of 2 in the Cryo-Em Structure of A Ras/Raf Complex (State 2)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of A Ras/Raf Complex (State 2) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn803 b:144.0 occ:1.00 SG A:CYS280 2.1 77.3 1.0 SG A:CYS261 2.1 90.5 1.0 ND1 A:HIS235 2.1 82.1 1.0 SG A:CYS264 2.1 82.8 1.0 CE1 A:HIS235 2.4 82.1 1.0 CB A:CYS264 2.8 82.8 1.0 CB A:CYS261 3.2 90.5 1.0 CB A:CYS280 3.3 77.3 1.0 CG A:HIS235 3.4 82.1 1.0 NE2 A:HIS235 3.6 82.1 1.0 N A:CYS264 3.7 82.8 1.0 CA A:CYS264 3.8 82.8 1.0 CA A:CYS280 3.8 77.3 1.0 CD2 A:HIS235 4.1 82.1 1.0 CA A:HIS235 4.2 82.1 1.0 CB A:HIS235 4.2 82.1 1.0 C A:CYS264 4.4 82.8 1.0 C A:CYS280 4.5 77.3 1.0 CA A:CYS261 4.6 90.5 1.0 CB A:TYR266 4.7 89.5 1.0 N A:GLY265 4.8 88.6 1.0 C A:THR263 4.9 80.1 1.0 CB A:THR263 4.9 80.1 1.0 CE1 A:PHE237 4.9 91.6 1.0 N A:TYR266 4.9 89.5 1.0

M.J.Eck, H.Jeon, E.Park, S.Rawson. Cryo-Em Structure of A Ras/Raf Complex To Be Published.