Atomistry » Zinc » PDB 8c8u-8cn6 » 8cg9
Atomistry »
  Zinc »
    PDB 8c8u-8cn6 »
      8cg9 »

Zinc in PDB 8cg9: Crystal Structure of Human Dna Cross-Link Repair 1A in Complex with A Cyclic N-Hydroxyurea Inhibitor

Enzymatic activity of Crystal Structure of Human Dna Cross-Link Repair 1A in Complex with A Cyclic N-Hydroxyurea Inhibitor

All present enzymatic activity of Crystal Structure of Human Dna Cross-Link Repair 1A in Complex with A Cyclic N-Hydroxyurea Inhibitor:
3.5.2.6;

Protein crystallography data

The structure of Crystal Structure of Human Dna Cross-Link Repair 1A in Complex with A Cyclic N-Hydroxyurea Inhibitor, PDB code: 8cg9 was solved by J.A.Newman, Y.Yosaatmadja, H.T.Baddock, M.Bielinski, F.Von Delft, C.Bountra, P.J.Mchugh, C.J.Schofield, O.Gileadi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 51.08 / 1.68
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 51.522, 57.148, 113.903, 90, 90, 90
R / Rfree (%) 22.3 / 23.1

Other elements in 8cg9:

The structure of Crystal Structure of Human Dna Cross-Link Repair 1A in Complex with A Cyclic N-Hydroxyurea Inhibitor also contains other interesting chemical elements:

Nickel (Ni) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of Human Dna Cross-Link Repair 1A in Complex with A Cyclic N-Hydroxyurea Inhibitor (pdb code 8cg9). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human Dna Cross-Link Repair 1A in Complex with A Cyclic N-Hydroxyurea Inhibitor, PDB code: 8cg9:

Zinc binding site 1 out of 1 in 8cg9

Go back to Zinc Binding Sites List in 8cg9
Zinc binding site 1 out of 1 in the Crystal Structure of Human Dna Cross-Link Repair 1A in Complex with A Cyclic N-Hydroxyurea Inhibitor


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human Dna Cross-Link Repair 1A in Complex with A Cyclic N-Hydroxyurea Inhibitor within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1104

b:28.8
occ:1.00
 NE2 A:HIS737 2.0 30.0 1.0
O A:HOH1234 2.1 23.2 1.0
O23 A:XOB1102 2.1 35.5 1.0
O23 A:R3Z1103 2.2 23.3 1.0
OD2 A:ASP815 2.2 21.4 1.0
O19 A:XOB1102 2.3 34.3 1.0
N20 A:XOB1102 3.0 33.5 1.0
N20 A:R3Z1103 3.0 29.8 1.0
C18 A:XOB1102 3.0 37.3 1.0
CD2 A:HIS737 3.0 30.3 1.0
CE1 A:HIS737 3.0 29.7 1.0
CG A:ASP815 3.1 24.8 1.0
OD1 A:ASP815 3.3 24.8 1.0
NI A:NI1101 3.3 21.1 1.0
O19 A:R3Z1103 3.6 27.3 1.0
C18 A:R3Z1103 3.6 30.5 1.0
O A:HOH1309 3.8 38.1 1.0
C21 A:R3Z1103 3.8 33.9 1.0
O A:HOH1270 3.9 33.4 1.0
O22 A:R3Z1103 4.0 28.6 1.0
ND1 A:HIS737 4.1 25.1 1.0
CG A:HIS737 4.2 30.0 1.0
CE1 A:HIS994 4.3 22.6 1.0
C21 A:XOB1102 4.3 38.8 1.0
NE2 A:HIS732 4.3 23.7 1.0
C17 A:XOB1102 4.4 41.3 1.0
NE2 A:HIS994 4.5 22.9 1.0
CB A:ASP815 4.5 20.1 1.0
CE1 A:HIS732 4.5 21.2 1.0
CB A:ASP736 4.6 36.6 1.0
OD2 A:ASP736 4.6 45.3 1.0
O22 A:XOB1102 4.8 36.9 1.0
C17 A:R3Z1103 4.8 34.4 1.0
ND1 A:HIS734 4.9 22.0 1.0
N12 A:R3Z1103 4.9 37.5 1.0
NE2 A:HIS793 5.0 20.7 1.0

Reference:

J.A.Newman, Y.Yosaatmadja, H.T.Baddock, M.Bielinski, F.Von Delft, C.Bountra, P.J.Mchugh, C.J.Schofield, O.Gileadi. Crystal Structure of Human Dna Cross-Link Repair 1A in Complex with A Cyclic N-Hydroxyurea Inhibitor To Be Published.
Page generated: Wed Oct 30 18:44:07 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy