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Zinc in PDB 8cew: Crystal Structure of Human Dna Cross-Link Repair 1A in Complex with N- Hydroxyimide Inhibitor H1

Enzymatic activity of Crystal Structure of Human Dna Cross-Link Repair 1A in Complex with N- Hydroxyimide Inhibitor H1

All present enzymatic activity of Crystal Structure of Human Dna Cross-Link Repair 1A in Complex with N- Hydroxyimide Inhibitor H1:
3.5.2.6;

Protein crystallography data

The structure of Crystal Structure of Human Dna Cross-Link Repair 1A in Complex with N- Hydroxyimide Inhibitor H1, PDB code: 8cew was solved by J.A.Newman, Y.Yosaatmadja, H.T.Baddock, M.Bielinski, F.Von Delft, C.Bountra, P.J.Mchugh, C.J.Schofield, O.Gileadi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 36.13 / 1.53
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 51.59, 56.5, 113.95, 90, 90, 90
R / Rfree (%) 19.8 / 22.4

Other elements in 8cew:

The structure of Crystal Structure of Human Dna Cross-Link Repair 1A in Complex with N- Hydroxyimide Inhibitor H1 also contains other interesting chemical elements:

Nickel (Ni) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of Human Dna Cross-Link Repair 1A in Complex with N- Hydroxyimide Inhibitor H1 (pdb code 8cew). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human Dna Cross-Link Repair 1A in Complex with N- Hydroxyimide Inhibitor H1, PDB code: 8cew:

Zinc binding site 1 out of 1 in 8cew

Go back to Zinc Binding Sites List in 8cew
Zinc binding site 1 out of 1 in the Crystal Structure of Human Dna Cross-Link Repair 1A in Complex with N- Hydroxyimide Inhibitor H1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human Dna Cross-Link Repair 1A in Complex with N- Hydroxyimide Inhibitor H1 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1103

b:23.1
occ:1.00
 OD2 A:ASP815 2.1 18.9 1.0
O3 A:UFI1105 2.1 27.1 1.0
O3 A:UFI1104 2.1 19.4 1.0
O A:HOH1240 2.2 23.6 1.0
NE2 A:HIS737 2.2 23.5 1.0
O4 A:UFI1105 2.2 23.6 1.0
C6 A:UFI1105 2.9 30.1 1.0
N1 A:UFI1105 2.9 28.4 1.0
N1 A:UFI1104 3.0 24.5 1.0
CG A:ASP815 3.1 22.2 1.0
CD2 A:HIS737 3.1 21.3 1.0
CE1 A:HIS737 3.2 21.4 1.0
OD1 A:ASP815 3.3 20.9 1.0
NI A:NI1102 3.3 18.8 1.0
C7 A:UFI1104 3.6 30.3 1.0
O2 A:UFI1104 3.7 22.4 1.0
C6 A:UFI1104 3.7 26.9 1.0
O A:HOH1273 3.8 25.2 1.0
O4 A:UFI1104 3.9 24.6 1.0
O A:HOH1426 4.1 36.4 1.0
C7 A:UFI1105 4.2 27.9 1.0
ND1 A:HIS737 4.3 20.8 1.0
NE2 A:HIS732 4.3 19.4 1.0
CG A:HIS737 4.3 24.3 1.0
C5 A:UFI1105 4.3 26.8 1.0
CE1 A:HIS994 4.3 20.5 1.0
CB A:ASP815 4.4 17.1 1.0
NE2 A:HIS994 4.5 20.8 1.0
CE1 A:HIS732 4.5 20.7 1.0
O2 A:UFI1105 4.8 30.7 1.0
C8 A:UFI1104 4.8 34.9 1.0
C5 A:UFI1104 4.9 29.1 1.0
C4 A:UFI1105 4.9 30.3 1.0
CB A:ASP736 5.0 26.9 1.0
ND1 A:HIS734 5.0 20.9 1.0

Reference:

J.A.Newman, Y.Yosaatmadja, H.T.Baddock, M.Bielinski, F.Von Delft, C.Bountra, P.J.Mchugh, C.J.Schofield, O.Gileadi. Crystal Structure of Human Dna Cross-Link Repair 1A in Complex with N-Hydroxyimide Inhibitor H1 To Be Published.
Page generated: Wed Oct 30 18:44:06 2024

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