Zinc in PDB 8cdk: CAND1 B-Hairpin++-Scf-SKP2 CAND1 Partly Engaged Scf Partly Rocked

The binding sites of Zinc atom in the CAND1 B-Hairpin++-Scf-SKP2 CAND1 Partly Engaged Scf Partly Rocked (pdb code 8cdk). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the CAND1 B-Hairpin++-Scf-SKP2 CAND1 Partly Engaged Scf Partly Rocked, PDB code: 8cdk:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the CAND1 B-Hairpin++-Scf-SKP2 CAND1 Partly Engaged Scf Partly Rocked


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of CAND1 B-Hairpin++-Scf-SKP2 CAND1 Partly Engaged Scf Partly Rocked within 5.0Å range: probe atom residue distance (Å) B Occ R:Zn201 b:83.8 occ:1.00 ND1 R:HIS80 2.0 76.8 1.0 SG R:CYS45 2.3 88.7 1.0 SG R:CYS42 2.3 85.6 1.0 SG R:CYS83 2.3 79.1 1.0 CB R:CYS42 2.8 85.6 1.0 CE1 R:HIS80 2.8 76.8 1.0 CG R:HIS80 3.2 76.8 1.0 CB R:CYS83 3.6 79.1 1.0 CB R:CYS45 3.6 88.7 1.0 CB R:HIS80 3.7 76.8 1.0 N R:CYS45 3.8 88.7 1.0 O R:CYS45 4.0 88.7 1.0 NE2 R:HIS80 4.0 76.8 1.0 CA R:CYS45 4.2 88.7 1.0 CD2 R:HIS80 4.2 76.8 1.0 N R:HIS80 4.3 76.8 1.0 CA R:CYS42 4.3 85.6 1.0 C R:CYS45 4.6 88.7 1.0 CA R:HIS80 4.6 76.8 1.0 CB R:ILE44 4.8 83.9 1.0 SG R:CYS53 4.9 97.2 1.0 C R:ILE44 4.9 83.9 1.0 C R:CYS42 4.9 85.6 1.0 CA R:CYS83 5.0 79.1 1.0

Zinc binding site 2 out of 3 in the CAND1 B-Hairpin++-Scf-SKP2 CAND1 Partly Engaged Scf Partly Rocked


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of CAND1 B-Hairpin++-Scf-SKP2 CAND1 Partly Engaged Scf Partly Rocked within 5.0Å range: probe atom residue distance (Å) B Occ R:Zn202 b:74.0 occ:1.00 OD2 R:ASP97 2.0 74.0 1.0 ND1 R:HIS77 2.0 63.2 1.0 SG R:CYS75 2.3 60.4 1.0 SG R:CYS94 2.3 72.6 1.0 CG R:ASP97 2.8 74.0 1.0 CB R:ASP97 2.9 74.0 1.0 CG R:HIS77 3.0 63.2 1.0 CE1 R:HIS77 3.0 63.2 1.0 CB R:CYS75 3.1 60.4 1.0 CB R:HIS77 3.3 63.2 1.0 CB R:CYS94 3.4 72.6 1.0 OD1 R:ASP97 4.0 74.0 1.0 NE2 R:HIS77 4.1 63.2 1.0 CD2 R:HIS77 4.1 63.2 1.0 CA R:ASP97 4.4 74.0 1.0 CA R:CYS75 4.4 60.4 1.0 O R:CYS75 4.5 60.4 1.0 CA R:HIS77 4.6 63.2 1.0 CE3 R:TRP101 4.6 62.2 1.0 C R:CYS75 4.6 60.4 1.0 CZ3 R:TRP101 4.6 62.2 1.0 N R:HIS77 4.7 63.2 1.0 CA R:CYS94 4.8 72.6 1.0 N R:ASP97 4.9 74.0 1.0 O R:ASP97 5.0 74.0 1.0

Zinc binding site 3 out of 3 in the CAND1 B-Hairpin++-Scf-SKP2 CAND1 Partly Engaged Scf Partly Rocked


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of CAND1 B-Hairpin++-Scf-SKP2 CAND1 Partly Engaged Scf Partly Rocked within 5.0Å range: probe atom residue distance (Å) B Occ R:Zn203 b:103.0 occ:1.00 ND1 R:HIS82 2.0 82.5 1.0 SG R:CYS56 2.3 100.8 1.0 SG R:CYS68 2.3 92.5 1.0 SG R:CYS53 2.3 97.2 1.0 CE1 R:HIS82 2.9 82.5 1.0 CB R:CYS53 2.9 97.2 1.0 CG R:HIS82 3.1 82.5 1.0 CB R:CYS68 3.6 92.5 1.0 CB R:HIS82 3.6 82.5 1.0 N R:CYS53 3.7 97.2 1.0 CB R:CYS56 3.8 100.8 1.0 CA R:CYS53 3.9 97.2 1.0 NE2 R:HIS82 4.0 82.5 1.0 CD2 R:HIS82 4.2 82.5 1.0 CA R:CYS68 4.4 92.5 1.0 C R:LEU52 4.8 92.8 1.0 N R:HIS82 4.9 82.5 1.0 CA R:HIS82 4.9 82.5 1.0 CA R:CYS56 5.0 100.8 1.0

K.Baek, D.C.Scott, L.T.Henneberg, M.T.King, M.Mann, B.A.Schulman. Systemwide Disassembly and Assembly of Scf Ubiquitin Ligase Complexes. Cell 2023.
ISSN: ISSN 1097-4172
PubMed: 37028429
DOI: 10.1016/J.CELL.2023.02.035