Zinc in PDB 8b9n: Crystal Structure of Nei Domain of Mouse NEIL3 Trapped in Covalent Complex with Ssdna with Abasic Site

All present enzymatic activity of Crystal Structure of Nei Domain of Mouse NEIL3 Trapped in Covalent Complex with Ssdna with Abasic Site:
4.2.99.18;

The structure of Crystal Structure of Nei Domain of Mouse NEIL3 Trapped in Covalent Complex with Ssdna with Abasic Site, PDB code: 8b9n was solved by M.Klima, E.Boura, J.Silhan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.22 / 2.00
Space group	P 41 2 2
Cell size a, b, c (Å), α, β, γ (°)	75.056, 75.056, 220.292, 90, 90, 90
R / Rfree (%)	23.9 / 27.8

The binding sites of Zinc atom in the Crystal Structure of Nei Domain of Mouse NEIL3 Trapped in Covalent Complex with Ssdna with Abasic Site (pdb code 8b9n). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Nei Domain of Mouse NEIL3 Trapped in Covalent Complex with Ssdna with Abasic Site, PDB code: 8b9n:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Nei Domain of Mouse NEIL3 Trapped in Covalent Complex with Ssdna with Abasic Site


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Nei Domain of Mouse NEIL3 Trapped in Covalent Complex with Ssdna with Abasic Site within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:31.0 occ:1.00 SG A:CYS277 2.3 28.2 1.0 SG A:CYS280 2.3 27.0 1.0 SG A:CYS258 2.3 30.0 1.0 SG A:CYS255 2.3 32.2 1.0 CB A:CYS255 3.2 34.7 1.0 CB A:CYS280 3.3 30.7 1.0 CB A:CYS277 3.4 27.4 1.0 CB A:CYS258 3.6 35.0 1.0 N A:CYS280 3.8 29.8 1.0 N A:CYS258 3.9 41.8 1.0 CA A:CYS280 4.2 34.4 1.0 ND1 A:HIS279 4.2 30.9 1.0 CA A:CYS258 4.3 41.1 1.0 CE1 A:PHE201 4.4 29.5 1.0 CB A:HIS279 4.5 31.5 1.0 CB A:GLN257 4.6 41.6 1.0 CA A:CYS255 4.6 38.6 1.0 C A:GLN257 4.8 46.1 1.0 CA A:CYS277 4.8 33.4 1.0 C A:HIS279 4.8 28.0 1.0 C A:CYS258 4.8 40.9 1.0 CG A:HIS279 4.9 31.0 1.0 OG A:SER260 4.9 34.1 1.0 N A:HIS259 4.9 39.8 1.0 CB A:SER260 4.9 29.5 1.0 N A:GLN257 4.9 42.9 1.0 CZ A:PHE201 5.0 29.1 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Nei Domain of Mouse NEIL3 Trapped in Covalent Complex with Ssdna with Abasic Site


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Nei Domain of Mouse NEIL3 Trapped in Covalent Complex with Ssdna with Abasic Site within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn401 b:35.8 occ:1.00 SG C:CYS277 2.3 33.3 1.0 SG C:CYS280 2.3 35.9 1.0 SG C:CYS255 2.3 39.0 1.0 SG C:CYS258 2.3 34.4 1.0 CB C:CYS255 3.2 42.9 1.0 CB C:CYS280 3.4 34.3 1.0 CB C:CYS277 3.5 36.9 1.0 CB C:CYS258 3.6 36.7 1.0 N C:CYS258 3.8 52.5 1.0 N C:CYS280 3.9 29.9 1.0 CA C:CYS280 4.2 36.3 1.0 ND1 C:HIS279 4.2 36.0 1.0 CA C:CYS258 4.2 46.2 1.0 CE1 C:PHE201 4.4 41.6 1.0 CB C:GLN257 4.6 53.0 1.0 CB C:HIS279 4.6 35.6 1.0 CA C:CYS255 4.6 43.5 1.0 C C:GLN257 4.7 52.8 1.0 CB C:SER260 4.8 37.8 1.0 OG C:SER260 4.8 39.9 1.0 C C:CYS258 4.8 47.9 1.0 N C:GLN257 4.9 51.2 1.0 CA C:CYS277 4.9 34.7 1.0 CG C:HIS279 4.9 38.5 1.0 C C:HIS279 4.9 34.6 1.0 CZ C:PHE201 4.9 45.4 1.0 N C:HIS259 4.9 43.7 1.0 CA C:GLN257 5.0 49.1 1.0

M.Klima, E.Boura, J.Silhan. Crystal Structure of Nei Domain of Mouse NEIL3 Trapped in Covalent Complex with Ssdna with Abasic Site To Be Published.