Zinc in PDB 7ysw: Cryo-Em Structure of FGF23-FGFR4-Aklotho-Hs Quaternary Complex

All present enzymatic activity of Cryo-Em Structure of FGF23-FGFR4-Aklotho-Hs Quaternary Complex:
2.7.10.1; 3.2.1.31;

The structure of Cryo-Em Structure of FGF23-FGFR4-Aklotho-Hs Quaternary Complex also contains other interesting chemical elements:

Copper

(Cu)

1 atom

The binding sites of Zinc atom in the Cryo-Em Structure of FGF23-FGFR4-Aklotho-Hs Quaternary Complex (pdb code 7ysw). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryo-Em Structure of FGF23-FGFR4-Aklotho-Hs Quaternary Complex, PDB code: 7ysw:

Zinc binding site 1 out of 1 in the Cryo-Em Structure of FGF23-FGFR4-Aklotho-Hs Quaternary Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of FGF23-FGFR4-Aklotho-Hs Quaternary Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:118.6 occ:1.00 OD1 A:ASP815 1.9 70.0 1.0 OD1 A:ASP426 2.0 67.6 1.0 OD2 A:ASP745 2.1 61.9 1.0 SG A:CYS739 2.3 62.5 1.0 CG A:ASP426 2.7 66.8 1.0 OD2 A:ASP426 2.8 69.6 1.0 CG A:ASP745 3.1 57.1 1.0 CG A:ASP815 3.1 68.5 1.0 OD1 A:ASP745 3.4 55.4 1.0 CB A:CYS739 3.5 53.6 1.0 OD2 A:ASP815 3.7 69.9 1.0 CB A:ALA428 3.9 47.5 1.0 N A:CYS739 4.0 53.2 1.0 CB A:ASP426 4.1 64.9 1.0 CB A:ASP815 4.3 58.5 1.0 CA A:CYS739 4.3 50.2 1.0 CB A:ALA738 4.4 44.2 1.0 CB A:ASP745 4.4 52.5 1.0 OG A:SER742 4.5 63.7 1.0 CB A:SER742 4.5 62.1 1.0 CA A:ASP815 4.6 50.6 1.0 NZ A:LYS744 4.7 62.0 1.0 N A:ALA428 4.7 52.3 1.0 CA A:ASP426 4.7 58.9 1.0 CA A:ALA428 4.8 43.0 1.0 N A:SER816 4.8 55.1 1.0 C A:ALA738 4.9 49.5 1.0 C A:ASP426 5.0 57.6 1.0

L.Chen, L.Fu, J.Sun, Z.Huang, M.Fang, A.Zinkle, X.Liu, J.Lu, Z.Pan, Y.Wang, G.Liang, X.Li, G.Chen, M.Mohammadi. Structural Basis For Fgf Hormone Signalling Nature 2023.
ISSN: ESSN 1476-4687
DOI: 10.1038/S41586-023-06155-9