Zinc in PDB 7wyj: Structure of the Complex of Lactoperoxidase with Nitric Oxide Catalytic Product Nitrite at 1.89 A Resolution

Enzymatic activity of Structure of the Complex of Lactoperoxidase with Nitric Oxide Catalytic Product Nitrite at 1.89 A Resolution

All present enzymatic activity of Structure of the Complex of Lactoperoxidase with Nitric Oxide Catalytic Product Nitrite at 1.89 A Resolution:
1.11.1.7;

Protein crystallography data

The structure of Structure of the Complex of Lactoperoxidase with Nitric Oxide Catalytic Product Nitrite at 1.89 A Resolution, PDB code: 7wyj was solved by V.Viswanathan, N.Pandey, A.K.Singh, M.Sinha, R.P.Singh, P.Sharma, P.Kaur, S.Sharma, T.P.Singh, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 35.30 / 1.89
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 53.99, 79.93, 76.31, 90, 102.18, 90
R / Rfree (%) 20.3 / 25.8

Other elements in 7wyj:

The structure of Structure of the Complex of Lactoperoxidase with Nitric Oxide Catalytic Product Nitrite at 1.89 A Resolution also contains other interesting chemical elements:

Iron (Fe) 1 atom
Calcium (Ca) 1 atom
Iodine (I) 38 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Structure of the Complex of Lactoperoxidase with Nitric Oxide Catalytic Product Nitrite at 1.89 A Resolution (pdb code 7wyj). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of the Complex of Lactoperoxidase with Nitric Oxide Catalytic Product Nitrite at 1.89 A Resolution, PDB code: 7wyj:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 7wyj

Go back to Zinc Binding Sites List in 7wyj
Zinc binding site 1 out of 2 in the Structure of the Complex of Lactoperoxidase with Nitric Oxide Catalytic Product Nitrite at 1.89 A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of the Complex of Lactoperoxidase with Nitric Oxide Catalytic Product Nitrite at 1.89 A Resolution within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn632

b:40.7
occ:0.50
ZN A:ZN632 0.0 40.7 0.5
O A:HOH746 1.9 44.1 1.0
O A:HOH733 2.5 41.8 1.0
OE2 A:GLU130 2.5 87.4 1.0
ZN A:ZN632 2.7 49.0 0.5
CA A:HIS426 2.8 65.8 1.0
CB A:HIS426 2.8 59.0 1.0
N A:LYS427 2.8 62.5 1.0
C A:HIS426 3.2 66.8 1.0
ND1 A:HIS426 3.6 59.8 1.0
CG A:HIS426 3.6 59.6 1.0
CD A:GLU130 3.7 82.8 1.0
CG1 A:ILE428 4.1 51.6 1.0
CA A:LYS427 4.1 62.0 1.0
N A:HIS426 4.1 68.0 1.0
N A:ILE428 4.2 50.9 1.0
CG A:GLU130 4.3 73.1 1.0
O A:HIS426 4.4 69.9 1.0
CB A:LYS427 4.4 65.6 1.0
CE1 A:PHE431 4.5 27.8 1.0
O A:THR425 4.5 76.2 1.0
CZ A:PHE431 4.6 28.0 1.0
CD1 A:ILE428 4.7 48.0 1.0
C A:LYS427 4.7 52.4 1.0
OE1 A:GLU130 4.7 87.9 1.0
C A:THR425 4.8 73.0 1.0
O A:HOH777 4.8 32.1 1.0
CG A:LYS427 4.8 68.1 1.0
CE1 A:HIS426 4.9 60.8 1.0
CD2 A:HIS426 4.9 57.2 1.0

Zinc binding site 2 out of 2 in 7wyj

Go back to Zinc Binding Sites List in 7wyj
Zinc binding site 2 out of 2 in the Structure of the Complex of Lactoperoxidase with Nitric Oxide Catalytic Product Nitrite at 1.89 A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of the Complex of Lactoperoxidase with Nitric Oxide Catalytic Product Nitrite at 1.89 A Resolution within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn632

b:49.0
occ:0.50
ZN A:ZN632 0.0 49.0 0.5
ND1 A:HIS426 1.9 59.8 1.0
OE2 A:GLU130 2.5 87.4 1.0
O A:HOH746 2.7 44.1 1.0
ZN A:ZN632 2.7 40.7 0.5
CE1 A:HIS426 2.8 60.8 1.0
CG A:HIS426 2.9 59.6 1.0
CG A:GLU130 2.9 73.1 1.0
CD A:GLU130 3.0 82.8 1.0
CG A:PRO159 3.3 28.4 1.0
CB A:HIS426 3.3 59.0 1.0
CB A:GLU130 3.3 66.3 1.0
CA A:HIS426 3.8 65.8 1.0
NE2 A:HIS426 3.8 58.0 1.0
CD2 A:HIS426 3.9 57.2 1.0
OE1 A:GLU130 4.1 87.9 1.0
CB A:PRO159 4.3 26.4 1.0
O A:HOH733 4.3 41.8 1.0
CD A:PRO159 4.3 28.1 1.0
CZ A:PHE431 4.3 28.0 1.0
CA A:GLU130 4.4 59.8 1.0
N A:HIS426 4.6 68.0 1.0
O A:THR425 4.6 76.2 1.0
C A:THR425 4.8 73.0 1.0
CE1 A:PHE431 5.0 27.8 1.0

Reference:

V.Viswanathan, N.Pandey, A.K.Singh, M.Sinha, R.P.Singh, P.Sharma, P.Kaur, S.Sharma, T.P.Singh. Structure of the Complex of Lactoperoxidase with Nitric Oxide Catalytic Product Nitrite at 1.89 A Resolution. To Be Published.
Page generated: Wed Oct 30 14:39:29 2024

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