Zinc in PDB 7uwh: Cryoem Structure of E. Coli Transcription-Coupled Ribonucleotide Excision Repair (Tc-Rer) Complex Bound to Ribonucleotide Substrate

All present enzymatic activity of Cryoem Structure of E. Coli Transcription-Coupled Ribonucleotide Excision Repair (Tc-Rer) Complex Bound to Ribonucleotide Substrate:
2.7.7.6; 3.1.26.4;

The structure of Cryoem Structure of E. Coli Transcription-Coupled Ribonucleotide Excision Repair (Tc-Rer) Complex Bound to Ribonucleotide Substrate also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Zinc atom in the Cryoem Structure of E. Coli Transcription-Coupled Ribonucleotide Excision Repair (Tc-Rer) Complex Bound to Ribonucleotide Substrate (pdb code 7uwh). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryoem Structure of E. Coli Transcription-Coupled Ribonucleotide Excision Repair (Tc-Rer) Complex Bound to Ribonucleotide Substrate, PDB code: 7uwh:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Cryoem Structure of E. Coli Transcription-Coupled Ribonucleotide Excision Repair (Tc-Rer) Complex Bound to Ribonucleotide Substrate


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryoem Structure of E. Coli Transcription-Coupled Ribonucleotide Excision Repair (Tc-Rer) Complex Bound to Ribonucleotide Substrate within 5.0Å range: probe atom residue distance (Å) B Occ J:Zn1501 b:84.8 occ:1.00 SG J:CYS70 1.9 50.1 1.0 SG J:CYS72 2.0 41.0 1.0 SG J:CYS85 2.4 42.6 1.0 SG J:CYS88 3.0 39.4 1.0 CB J:CYS85 3.0 42.6 1.0 CB J:CYS70 3.5 50.1 1.0 CB J:CYS72 3.5 41.0 1.0 N J:CYS72 3.6 41.0 1.0 CA J:CYS72 4.1 41.0 1.0 CB J:LYS74 4.1 44.6 1.0 N J:LEU71 4.3 38.9 1.0 N J:GLY73 4.5 38.8 1.0 CA J:CYS85 4.5 42.6 1.0 N J:LYS74 4.5 44.6 1.0 C J:CYS72 4.6 41.0 1.0 CB J:CYS88 4.6 39.4 1.0 N J:CYS88 4.6 39.4 1.0 CA J:CYS70 4.6 50.1 1.0 C J:CYS70 4.7 50.1 1.0 C J:LEU71 4.7 38.9 1.0 CB J:LYS87 4.9 42.0 1.0 CA J:LEU71 4.9 38.9 1.0 CA J:LYS74 5.0 44.6 1.0

Zinc binding site 2 out of 2 in the Cryoem Structure of E. Coli Transcription-Coupled Ribonucleotide Excision Repair (Tc-Rer) Complex Bound to Ribonucleotide Substrate


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryoem Structure of E. Coli Transcription-Coupled Ribonucleotide Excision Repair (Tc-Rer) Complex Bound to Ribonucleotide Substrate within 5.0Å range: probe atom residue distance (Å) B Occ J:Zn1502 b:34.5 occ:1.00 SG J:CYS888 2.1 14.1 1.0 SG J:CYS895 2.3 10.6 1.0 SG J:CYS898 2.4 10.6 1.0 SG J:CYS814 2.5 20.3 1.0 CB J:CYS888 3.0 14.1 1.0 CB J:CYS898 3.1 10.6 1.0 CB J:CYS895 3.4 10.6 1.0 CB J:CYS814 3.4 20.3 1.0 CA J:CYS888 3.5 14.1 1.0 N J:CYS895 4.0 10.6 1.0 OG1 J:THR890 4.0 16.0 1.0 N J:ASP889 4.1 16.7 1.0 N J:CYS898 4.1 10.6 1.0 NH2 J:ARG883 4.2 12.8 1.0 CA J:CYS898 4.2 10.6 1.0 N J:CYS814 4.2 20.3 1.0 CA J:CYS895 4.2 10.6 1.0 C J:CYS888 4.3 14.1 1.0 CA J:CYS814 4.5 20.3 1.0 OG1 J:THR816 4.6 23.1 1.0 O J:CYS895 4.7 10.6 1.0 N J:CYS888 4.7 14.1 1.0 C J:CYS895 4.8 10.6 1.0 NE J:ARG883 4.8 12.8 1.0 CZ J:ARG883 4.8 12.8 1.0 N J:THR890 4.8 16.0 1.0 CB J:THR890 5.0 16.0 1.0

Z.Hao, M.Gowder, S.Proshkin, B.K.Bharati, V.Epshtein, V.Svetlov, I.Shamovsky, E.Nudler. Rna Polymerase Drives Ribonucleotide Excision Dna Repair in E. Coli. Cell 2023.
ISSN: ISSN 1097-4172
PubMed: 37196657
DOI: 10.1016/J.CELL.2023.04.029