Zinc in PDB 7uwe: Cryoem Structure of E. Coli Transcription-Coupled Ribonucleotide Excision Repair (Tc-Rer) Complex

All present enzymatic activity of Cryoem Structure of E. Coli Transcription-Coupled Ribonucleotide Excision Repair (Tc-Rer) Complex:
2.7.7.6; 3.1.26.4;

The structure of Cryoem Structure of E. Coli Transcription-Coupled Ribonucleotide Excision Repair (Tc-Rer) Complex also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Zinc atom in the Cryoem Structure of E. Coli Transcription-Coupled Ribonucleotide Excision Repair (Tc-Rer) Complex (pdb code 7uwe). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryoem Structure of E. Coli Transcription-Coupled Ribonucleotide Excision Repair (Tc-Rer) Complex, PDB code: 7uwe:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Cryoem Structure of E. Coli Transcription-Coupled Ribonucleotide Excision Repair (Tc-Rer) Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryoem Structure of E. Coli Transcription-Coupled Ribonucleotide Excision Repair (Tc-Rer) Complex within 5.0Å range: probe atom residue distance (Å) B Occ J:Zn1502 b:125.8 occ:1.00 SG J:CYS72 2.3 59.7 1.0 SG J:CYS70 2.3 58.1 1.0 N J:LYS74 2.3 67.2 1.0 N J:GLY73 2.4 65.4 1.0 CB J:CYS70 2.5 58.1 1.0 C J:CYS72 2.8 59.7 1.0 N J:CYS72 3.0 59.7 1.0 CA J:CYS72 3.1 59.7 1.0 C J:GLY73 3.1 65.4 1.0 CA J:GLY73 3.1 65.4 1.0 CB J:CYS72 3.3 59.7 1.0 CB J:LYS74 3.3 67.2 1.0 CA J:LYS74 3.3 67.2 1.0 O J:CYS72 3.6 59.7 1.0 CA J:CYS70 3.6 58.1 1.0 C J:CYS70 3.7 58.1 1.0 N J:LEU71 3.9 52.9 1.0 C J:LEU71 4.0 52.9 1.0 O J:CYS70 4.1 58.1 1.0 O J:GLY73 4.3 65.4 1.0 N J:TYR75 4.3 70.3 1.0 C J:LYS74 4.4 67.2 1.0 N J:CYS70 4.5 58.1 1.0 SG J:CYS85 4.6 54.5 1.0 CA J:LEU71 4.6 52.9 1.0 SG J:CYS88 4.7 54.9 1.0 CG J:LYS74 4.7 67.2 1.0 O J:LEU71 4.9 52.9 1.0

Zinc binding site 2 out of 2 in the Cryoem Structure of E. Coli Transcription-Coupled Ribonucleotide Excision Repair (Tc-Rer) Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryoem Structure of E. Coli Transcription-Coupled Ribonucleotide Excision Repair (Tc-Rer) Complex within 5.0Å range: probe atom residue distance (Å) B Occ J:Zn1503 b:35.2 occ:1.00 SG J:CYS895 2.3 10.3 1.0 SG J:CYS898 2.3 10.1 1.0 SG J:CYS814 2.3 22.2 1.0 SG J:CYS888 2.3 15.9 1.0 NH2 J:ARG883 3.0 17.5 1.0 CB J:CYS888 3.2 15.9 1.0 CB J:CYS814 3.2 22.2 1.0 CB J:CYS898 3.4 10.1 1.0 CB J:CYS895 3.7 10.3 1.0 CA J:CYS888 3.7 15.9 1.0 OG1 J:THR890 4.1 17.3 1.0 N J:CYS814 4.2 22.2 1.0 CZ J:ARG883 4.2 17.5 1.0 N J:ASP889 4.3 21.3 1.0 N J:CYS898 4.3 10.1 1.0 N J:CYS895 4.3 10.3 1.0 CA J:CYS814 4.3 22.2 1.0 OG1 J:THR816 4.4 31.1 1.0 CA J:CYS898 4.5 10.1 1.0 CA J:CYS895 4.5 10.3 1.0 C J:CYS888 4.5 15.9 1.0 NE J:ARG883 4.7 17.5 1.0 N J:CYS888 4.9 15.9 1.0 C J:CYS895 5.0 10.3 1.0

Z.Hao, M.Gowder, S.Proshkin, B.K.Bharati, V.Epshtein, V.Svetlov, I.Shamovsky, E.Nudler. Rna Polymerase Drives Ribonucleotide Excision Dna Repair in E. Coli. Cell 2023.
ISSN: ISSN 1097-4172
PubMed: 37196657
DOI: 10.1016/J.CELL.2023.04.029