Zinc in PDB 7qsn: Bovine Complex I in Lipid Nanodisc, Deactive-Apo

All present enzymatic activity of Bovine Complex I in Lipid Nanodisc, Deactive-Apo:
1.6.5.3; 1.6.99.3; 7.1.1.2;

The structure of Bovine Complex I in Lipid Nanodisc, Deactive-Apo also contains other interesting chemical elements:

Magnesium	(Mg)	1 atom
Potassium	(K)	1 atom
Iron	(Fe)	28 atoms

The binding sites of Zinc atom in the Bovine Complex I in Lipid Nanodisc, Deactive-Apo (pdb code 7qsn). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Bovine Complex I in Lipid Nanodisc, Deactive-Apo, PDB code: 7qsn:

Zinc binding site 1 out of 1 in the Bovine Complex I in Lipid Nanodisc, Deactive-Apo


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Bovine Complex I in Lipid Nanodisc, Deactive-Apo within 5.0Å range: probe atom residue distance (Å) B Occ R:Zn201 b:45.4 occ:1.00 NE2 R:HIS68 2.0 28.4 1.0 SG R:CYS84 2.2 30.8 1.0 SG R:CYS87 2.2 30.1 1.0 SG R:CYS59 2.4 30.3 1.0 CE1 R:HIS68 2.9 28.4 1.0 CD2 R:HIS68 3.0 28.4 1.0 CB R:CYS84 3.2 30.8 1.0 CB R:CYS87 3.3 30.1 1.0 CB R:CYS59 3.5 30.3 1.0 N R:GLY61 3.7 30.4 1.0 CA R:GLY61 3.8 30.4 1.0 N R:CYS87 3.8 30.1 1.0 ND1 R:HIS68 4.0 28.4 1.0 CG R:HIS68 4.1 28.4 1.0 CA R:CYS87 4.1 30.1 1.0 C R:CYS59 4.4 30.3 1.0 CB R:TYR86 4.5 28.0 1.0 C R:ASP60 4.6 30.6 1.0 CA R:CYS59 4.6 30.3 1.0 O R:CYS59 4.6 30.3 1.0 CA R:CYS84 4.6 30.8 1.0 N R:ASP60 4.7 30.6 1.0 C R:TYR86 4.8 28.0 1.0 C R:CYS87 4.8 30.1 1.0 N R:GLY88 4.9 30.5 1.0 N R:TYR86 5.0 28.0 1.0

I.Chung, J.J.Wright, H.R.Bridges, B.S.Ivanov, O.Biner, C.S.Pereira, G.M.Arantes, J.Hirst. Cryo-Em Structures Define Ubiquinone-10 Binding to Mitochondrial Complex I and Conformational Transitions Accompanying Q-Site Occupancy. Nat Commun V. 13 2758 2022.
ISSN: ESSN 2041-1723
PubMed: 35589726
DOI: 10.1038/S41467-022-30506-1