Zinc in PDB 7q0j: Rna Polymerase Elongation Complex in More-Swiveled Conformation

All present enzymatic activity of Rna Polymerase Elongation Complex in More-Swiveled Conformation:
2.7.7.6;

The structure of Rna Polymerase Elongation Complex in More-Swiveled Conformation also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Zinc atom in the Rna Polymerase Elongation Complex in More-Swiveled Conformation (pdb code 7q0j). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Rna Polymerase Elongation Complex in More-Swiveled Conformation, PDB code: 7q0j:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Rna Polymerase Elongation Complex in More-Swiveled Conformation


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Rna Polymerase Elongation Complex in More-Swiveled Conformation within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1501 b:331.4 occ:1.00 N D:CYS88 2.3 247.2 1.0 SG D:CYS85 2.5 251.9 1.0 SG D:CYS72 2.5 224.2 1.0 SG D:CYS88 2.5 247.2 1.0 CB D:CYS85 2.7 251.9 1.0 CB D:CYS88 3.0 247.2 1.0 CA D:CYS88 3.2 247.2 1.0 N D:LYS87 3.2 266.1 1.0 C D:LYS87 3.3 266.1 1.0 CB D:LYS87 3.4 266.1 1.0 CB D:CYS72 3.5 224.2 1.0 CA D:LYS87 3.5 266.1 1.0 N D:GLY89 3.6 222.2 1.0 C D:CYS88 3.9 247.2 1.0 N D:GLU86 3.9 266.4 1.0 CA D:CYS85 4.0 251.9 1.0 C D:CYS85 4.1 251.9 1.0 C D:GLU86 4.3 266.4 1.0 N D:CYS72 4.3 224.2 1.0 CG D:LYS87 4.3 266.1 1.0 CB D:CYS70 4.4 220.8 1.0 O D:LYS87 4.5 266.1 1.0 CA D:CYS72 4.5 224.2 1.0 CA D:GLU86 4.7 266.4 1.0 N D:CYS85 4.7 251.9 1.0 CA D:GLY89 4.8 222.2 1.0 O D:CYS85 4.9 251.9 1.0 SG D:CYS70 5.0 220.8 1.0

Zinc binding site 2 out of 2 in the Rna Polymerase Elongation Complex in More-Swiveled Conformation


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Rna Polymerase Elongation Complex in More-Swiveled Conformation within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1502 b:258.4 occ:1.00 SG D:CYS888 2.4 192.1 1.0 SG D:CYS814 2.4 198.6 1.0 SG D:CYS895 2.4 177.6 1.0 CB D:CYS814 2.5 198.6 1.0 CB D:CYS888 3.3 192.1 1.0 N D:ASP889 3.3 201.6 1.0 CA D:CYS888 3.3 192.1 1.0 CB D:CYS895 3.5 177.6 1.0 SG D:CYS898 3.5 173.8 1.0 OG1 D:THR890 3.7 187.3 1.0 C D:CYS888 3.8 192.1 1.0 CA D:CYS814 3.9 198.6 1.0 N D:CYS814 4.1 198.6 1.0 NH2 D:ARG883 4.2 168.6 1.0 N D:CYS895 4.2 177.6 1.0 CB D:CYS898 4.3 173.8 1.0 CA D:ASP889 4.4 201.6 1.0 CA D:CYS895 4.4 177.6 1.0 N D:THR890 4.5 187.3 1.0 C D:ASP889 4.5 201.6 1.0 N D:CYS888 4.6 192.1 1.0 OG1 D:THR816 4.6 189.3 1.0 CB D:THR890 4.7 187.3 1.0 C D:CYS814 4.9 198.6 1.0 CB D:ASP889 5.0 201.6 1.0 O D:CYS888 5.0 192.1 1.0

C.Zhu, X.Guo, P.Dumas, M.Takacs, M.Abdelkareem, A.Vanden Broeck, C.Saint-Andre, G.Papai, C.Crucifix, J.Ortiz, A.Weixlbaumer. Transcription Factors Modulate Rna Polymerase Conformational Equilibrium. Nat Commun V. 13 1546 2022.
ISSN: ESSN 2041-1723
PubMed: 35318334
DOI: 10.1038/S41467-022-29148-0