Zinc in PDB 7py3: Cryoem Structure of E.Coli Rna Polymerase Elongation Complex Bound to Nusa (the Consensus Nusa-Ec)

All present enzymatic activity of Cryoem Structure of E.Coli Rna Polymerase Elongation Complex Bound to Nusa (the Consensus Nusa-Ec):
2.7.7.6;

The structure of Cryoem Structure of E.Coli Rna Polymerase Elongation Complex Bound to Nusa (the Consensus Nusa-Ec) also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Zinc atom in the Cryoem Structure of E.Coli Rna Polymerase Elongation Complex Bound to Nusa (the Consensus Nusa-Ec) (pdb code 7py3). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryoem Structure of E.Coli Rna Polymerase Elongation Complex Bound to Nusa (the Consensus Nusa-Ec), PDB code: 7py3:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Cryoem Structure of E.Coli Rna Polymerase Elongation Complex Bound to Nusa (the Consensus Nusa-Ec)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryoem Structure of E.Coli Rna Polymerase Elongation Complex Bound to Nusa (the Consensus Nusa-Ec) within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1502 b:183.3 occ:1.00 SG D:CYS88 2.3 154.7 1.0 SG D:CYS72 2.3 163.0 1.0 SG D:CYS70 2.3 155.5 1.0 N D:CYS72 2.5 163.0 1.0 CB D:CYS70 2.5 155.5 1.0 CB D:CYS72 3.1 163.0 1.0 CA D:CYS72 3.1 163.0 1.0 N D:LEU71 3.2 153.2 1.0 N D:GLY73 3.3 159.1 1.0 C D:CYS70 3.4 155.5 1.0 C D:CYS72 3.5 163.0 1.0 CA D:CYS70 3.5 155.5 1.0 C D:LEU71 3.6 153.2 1.0 N D:LYS74 3.8 157.5 1.0 CA D:LEU71 3.9 153.2 1.0 O D:CYS70 4.0 155.5 1.0 CB D:CYS88 4.1 154.7 1.0 CB D:LYS74 4.3 157.5 1.0 O D:CYS88 4.3 154.7 1.0 CA D:GLY73 4.4 159.1 1.0 O D:CYS72 4.4 163.0 1.0 SG D:CYS85 4.5 157.3 1.0 CB D:LEU71 4.5 153.2 1.0 CB D:CYS85 4.6 157.3 1.0 N D:CYS70 4.6 155.5 1.0 C D:GLY73 4.6 159.1 1.0 O D:LEU71 4.7 153.2 1.0 CA D:LYS74 4.7 157.5 1.0 N D:CYS88 4.9 154.7 1.0 CA D:CYS88 4.9 154.7 1.0

Zinc binding site 2 out of 2 in the Cryoem Structure of E.Coli Rna Polymerase Elongation Complex Bound to Nusa (the Consensus Nusa-Ec)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryoem Structure of E.Coli Rna Polymerase Elongation Complex Bound to Nusa (the Consensus Nusa-Ec) within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1503 b:120.1 occ:1.00 CB D:CYS895 2.2 101.0 1.0 SG D:CYS888 2.3 108.6 1.0 SG D:CYS895 2.3 101.0 1.0 SG D:CYS898 2.3 99.1 1.0 CB D:CYS814 2.9 111.4 1.0 CB D:CYS898 3.0 99.1 1.0 CB D:CYS888 3.1 108.6 1.0 SG D:CYS814 3.4 111.4 1.0 CA D:CYS895 3.6 101.0 1.0 CA D:CYS888 3.9 108.6 1.0 N D:CYS895 4.0 101.0 1.0 CA D:CYS814 4.0 111.4 1.0 N D:CYS814 4.3 111.4 1.0 CA D:CYS898 4.4 99.1 1.0 C D:CYS895 4.4 101.0 1.0 O D:CYS895 4.5 101.0 1.0 N D:CYS898 4.6 99.1 1.0 N D:ASP889 4.6 117.2 1.0 O D:SER887 4.7 100.8 1.0 C D:CYS888 4.8 108.6 1.0

C.Zhu, X.Guo, P.Dumas, M.Takacs, M.Abdelkareem, A.Vanden Broeck, C.Saint-Andre, G.Papai, C.Crucifix, J.Ortiz, A.Weixlbaumer. Transcription Factors Modulate Rna Polymerase Conformational Equilibrium. Nat Commun V. 13 1546 2022.
ISSN: ESSN 2041-1723
PubMed: 35318334
DOI: 10.1038/S41467-022-29148-0