Zinc in PDB 7oi6: Cryo-Em Structure of Late Human 39S Mitoribosome Assembly Intermediates, State 1

All present enzymatic activity of Cryo-Em Structure of Late Human 39S Mitoribosome Assembly Intermediates, State 1:
3.1.1.29; 3.6.4.13;

The structure of Cryo-Em Structure of Late Human 39S Mitoribosome Assembly Intermediates, State 1 also contains other interesting chemical elements:

Magnesium

(Mg)

48 atoms

The binding sites of Zinc atom in the Cryo-Em Structure of Late Human 39S Mitoribosome Assembly Intermediates, State 1 (pdb code 7oi6). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryo-Em Structure of Late Human 39S Mitoribosome Assembly Intermediates, State 1, PDB code: 7oi6:

Zinc binding site 1 out of 1 in the Cryo-Em Structure of Late Human 39S Mitoribosome Assembly Intermediates, State 1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Late Human 39S Mitoribosome Assembly Intermediates, State 1 within 5.0Å range: probe atom residue distance (Å) B Occ 0:Zn200 b:5.0 occ:1.00 N 0:CYS126 2.1 5.0 1.0 CB 0:CYS123 2.5 5.0 1.0 CB 0:CYS113 2.5 5.0 1.0 CB 0:CYS126 2.6 5.0 1.0 CA 0:CYS126 2.9 5.0 1.0 C 0:CYS123 3.0 5.0 1.0 O 0:CYS123 3.0 5.0 1.0 N 0:TYR125 3.2 10.4 1.0 C 0:TYR125 3.2 10.4 1.0 CA 0:CYS123 3.3 5.0 1.0 CA 0:TYR125 3.5 10.4 1.0 N 0:ALA124 3.5 5.0 1.0 CB 0:TYR125 3.6 10.4 1.0 C 0:ALA124 3.9 5.0 1.0 CA 0:CYS113 3.9 5.0 1.0 C 0:CYS126 4.1 5.0 1.0 N 0:TYR127 4.2 5.0 1.0 CA 0:ALA124 4.3 5.0 1.0 O 0:TYR125 4.3 10.4 1.0 N 0:CYS123 4.4 5.0 1.0 O 0:CYS113 4.5 5.0 1.0 O 0:ALA124 4.6 5.0 1.0 C 0:CYS113 4.6 5.0 1.0 N 0:CYS113 4.9 5.0 1.0

J.Cheng, O.Berninghausen, R.Beckmann. A Distinct Assembly Pathway of the Human 39S Late Pre-Mitoribosome. Nat Commun V. 12 4544 2021.
ISSN: ESSN 2041-1723
PubMed: 34315873
DOI: 10.1038/S41467-021-24818-X