Zinc in PDB 7eqx: Crystal Structure of An Aedes Aegypti Procarboxypeptidase B1

All present enzymatic activity of Crystal Structure of An Aedes Aegypti Procarboxypeptidase B1:
3.4.17.2;

The structure of Crystal Structure of An Aedes Aegypti Procarboxypeptidase B1, PDB code: 7eqx was solved by Y.K.Choong, E.Gavor, C.Jobichen, J.Sivaraman, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	33.63 / 2.08
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	139.797, 74.436, 83.108, 90, 119.08, 90
R / Rfree (%)	16.8 / 19.8

The binding sites of Zinc atom in the Crystal Structure of An Aedes Aegypti Procarboxypeptidase B1 (pdb code 7eqx). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of An Aedes Aegypti Procarboxypeptidase B1, PDB code: 7eqx:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of An Aedes Aegypti Procarboxypeptidase B1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of An Aedes Aegypti Procarboxypeptidase B1 within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn401 b:25.0 occ:1.00 OE2 C:GLU71 2.1 15.1 1.0 OE1 C:GLU71 2.1 13.7 1.0 ND1 C:HIS68 2.3 18.5 1.0 ND1 C:HIS192 2.3 20.5 1.0 CD C:GLU71 2.4 11.2 1.0 CE1 C:HIS68 3.2 18.2 1.0 CG C:HIS192 3.2 19.1 1.0 CG C:HIS68 3.3 16.7 1.0 CE1 C:HIS192 3.3 20.3 1.0 CB C:HIS192 3.4 17.6 1.0 CB C:HIS68 3.6 14.7 1.0 O C:HOH603 3.9 18.5 1.0 CG C:GLU71 3.9 16.2 1.0 O C:SER193 4.3 20.6 1.0 CA C:HIS192 4.3 18.9 1.0 NE2 C:HIS68 4.3 21.1 1.0 CD2 C:HIS192 4.4 18.9 1.0 NE2 C:HIS192 4.4 21.0 1.0 CD2 C:HIS68 4.4 16.4 1.0 NH1 C:ARG123 4.4 26.9 1.0 O C:HOH558 4.5 20.8 1.0 N C:SER193 4.5 16.3 1.0 OE2 C:GLU267 4.8 32.9 1.0 CB C:GLU71 4.8 16.4 1.0 CA C:HIS68 4.9 14.9 1.0 OE1 C:GLU267 5.0 23.3 1.0 O C:HOH662 5.0 31.9 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of An Aedes Aegypti Procarboxypeptidase B1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of An Aedes Aegypti Procarboxypeptidase B1 within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn401 b:22.7 occ:1.00 OE2 D:GLU71 2.1 14.5 1.0 OE1 D:GLU71 2.1 14.0 1.0 O D:HOH684 2.1 24.1 1.0 ND1 D:HIS68 2.3 21.0 1.0 ND1 D:HIS192 2.3 19.3 1.0 CD D:GLU71 2.4 13.8 1.0 CG D:HIS192 3.2 18.8 1.0 CG D:HIS68 3.2 17.3 1.0 CE1 D:HIS68 3.3 15.2 1.0 CE1 D:HIS192 3.3 21.5 1.0 CB D:HIS192 3.4 15.3 1.0 CB D:HIS68 3.5 17.6 1.0 O D:HOH569 3.8 18.8 1.0 CG D:GLU71 3.9 16.0 1.0 O D:SER193 4.3 16.7 1.0 CA D:HIS192 4.4 17.8 1.0 NH1 D:ARG123 4.4 24.9 1.0 NE2 D:HIS68 4.4 15.9 1.0 CD2 D:HIS192 4.4 20.7 1.0 NE2 D:HIS192 4.4 22.9 1.0 CD2 D:HIS68 4.4 14.9 1.0 O D:HOH561 4.4 21.6 1.0 N D:SER193 4.5 18.9 1.0 O D:HOH632 4.7 31.2 1.0 CA D:HIS68 4.8 15.6 1.0 CB D:GLU71 4.8 14.2 1.0 OE1 D:GLU267 4.9 22.5 1.0 OE2 D:GLU267 4.9 32.0 1.0 N D:HIS68 5.0 12.2 1.0

Y.K.Choong, E.Gavor, C.Jobichen, J.Sivaraman. Crystal Structure of An Aedes Aegypti Procarboxypeptidase B1 To Be Published.