Zinc in PDB 7ebj: Apo Structure of the Mouse TRIM66 Phd-Bromo Dual Domain

The structure of Apo Structure of the Mouse TRIM66 Phd-Bromo Dual Domain, PDB code: 7ebj was solved by Z.Wang, J.Jiang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.22 / 1.80
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	80.073, 80.073, 80.046, 90, 90, 90
R / Rfree (%)	18.3 / 21.2

The binding sites of Zinc atom in the Apo Structure of the Mouse TRIM66 Phd-Bromo Dual Domain (pdb code 7ebj). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Apo Structure of the Mouse TRIM66 Phd-Bromo Dual Domain, PDB code: 7ebj:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Apo Structure of the Mouse TRIM66 Phd-Bromo Dual Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Apo Structure of the Mouse TRIM66 Phd-Bromo Dual Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1201 b:25.0 occ:1.00 ND1 A:HIS1019 2.2 25.7 1.0 SG A:CYS1002 2.3 25.3 1.0 SG A:CYS1022 2.3 24.1 1.0 SG A:CYS999 2.3 21.7 1.0 CB A:CYS999 2.9 26.2 1.0 CE1 A:HIS1019 3.1 30.2 1.0 CG A:HIS1019 3.2 27.6 1.0 CB A:CYS1022 3.2 23.4 1.0 CB A:CYS1002 3.3 25.8 1.0 CB A:HIS1019 3.5 25.8 1.0 N A:CYS1002 3.8 24.1 1.0 N A:HIS1019 4.1 22.3 1.0 CA A:CYS1002 4.1 25.2 1.0 NE2 A:HIS1019 4.2 27.7 1.0 CD2 A:HIS1019 4.3 25.3 1.0 CA A:HIS1019 4.4 24.2 1.0 CA A:CYS999 4.4 26.5 1.0 CA A:CYS1022 4.6 21.1 1.0 CB A:VAL1001 4.7 18.6 1.0 O A:HOH1492 4.8 28.5 1.0 C A:CYS1002 4.8 27.2 1.0 C A:VAL1001 4.9 23.0 1.0 N A:ILE1003 5.0 24.4 1.0

Zinc binding site 2 out of 2 in the Apo Structure of the Mouse TRIM66 Phd-Bromo Dual Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Apo Structure of the Mouse TRIM66 Phd-Bromo Dual Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1202 b:23.4 occ:1.00 SG A:CYS1040 2.3 26.7 1.0 SG A:CYS1011 2.3 22.3 1.0 SG A:CYS1014 2.3 25.4 1.0 SG A:CYS1037 2.4 21.5 1.0 CB A:CYS1011 3.2 21.4 1.0 CB A:CYS1014 3.3 24.2 1.0 CB A:CYS1040 3.4 25.2 1.0 CB A:CYS1037 3.5 23.4 1.0 N A:CYS1014 3.9 23.0 1.0 N A:CYS1037 4.0 22.4 1.0 CA A:CYS1014 4.1 22.8 1.0 N A:CYS1040 4.2 24.8 1.0 CA A:CYS1037 4.2 20.5 1.0 O A:HOH1391 4.3 29.8 1.0 CA A:CYS1040 4.4 27.2 1.0 C A:ARG1013 4.6 24.2 1.0 CA A:CYS1011 4.6 22.0 1.0 O A:HOH1483 4.7 37.0 1.0 C A:CYS1037 4.7 22.0 1.0 O A:CYS1037 4.7 22.1 1.0 C A:CYS1014 4.7 23.9 1.0 O A:CYS1014 4.8 25.1 1.0 CB A:ARG1013 4.8 23.6 1.0 OH A:TYR1018 4.9 20.7 1.0 N A:ARG1013 4.9 21.7 1.0 CB A:LEU1039 5.0 21.4 1.0 CA A:ARG1013 5.0 23.3 1.0

F.Zuo, J.Jiang, H.Fu, K.Yan, R.Liefke, J.Zhang, Y.Hong, Z.Chang, N.Liu, Z.Wang, Q.Xi. A TRIM66/DAX1/Dux Axis Suppresses the Totipotent 2-Cell-Like State in Murine Embryonic Stem Cells. Cell Stem Cell V. 29 948 2022.
ISSN: ISSN 1875-9777
PubMed: 35659877
DOI: 10.1016/J.STEM.2022.05.004