Atomistry » Zinc » PDB 7ae7-7ao9 » 7aea
Atomistry »
  Zinc »
    PDB 7ae7-7ao9 »
      7aea »

Zinc in PDB 7aea: Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2

Enzymatic activity of Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2

All present enzymatic activity of Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2:
2.7.7.6;

Other elements in 7aea:

The structure of Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2 also contains other interesting chemical elements:

Iron (Fe) 4 atoms
Magnesium (Mg) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2 (pdb code 7aea). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 7 binding sites of Zinc where determined in the Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2, PDB code: 7aea:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6; 7;

Zinc binding site 1 out of 7 in 7aea

Go back to Zinc Binding Sites List in 7aea
Zinc binding site 1 out of 7 in the Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1401

b:134.8
occ:1.00
 SG A:CYS79 2.5 117.5 1.0
SG A:CYS69 2.5 139.0 1.0
CB A:CYS69 3.1 139.0 1.0
SG A:CYS72 3.2 129.5 1.0
O A:CYS72 3.3 129.5 1.0
CE1 A:HIS82 3.4 117.8 1.0
ND1 A:HIS82 3.5 117.8 1.0
CB A:CYS79 3.6 117.5 1.0
N A:CYS72 3.7 129.5 1.0
C A:CYS72 4.2 129.5 1.0
CA A:GLY61 4.3 129.3 1.0
CA A:CYS72 4.3 129.5 1.0
CB A:CYS72 4.3 129.5 1.0
CB A:THR71 4.5 131.2 1.0
CA A:CYS69 4.6 139.0 1.0
N A:THR71 4.6 131.2 1.0
N A:GLY61 4.6 129.3 1.0
NE2 A:HIS82 4.6 117.8 1.0
C A:THR71 4.8 131.2 1.0
CG A:HIS82 4.8 117.8 1.0
CA A:THR71 4.9 131.2 1.0
CA A:CYS79 4.9 117.5 1.0
N A:GLU70 4.9 133.8 1.0
C A:CYS69 4.9 139.0 1.0

Zinc binding site 2 out of 7 in 7aea

Go back to Zinc Binding Sites List in 7aea
Zinc binding site 2 out of 7 in the Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1402

b:167.6
occ:1.00
 SG A:CYS159 2.5 154.3 1.0
SG A:CYS112 2.5 145.2 1.0
SG A:CYS109 2.6 139.6 1.0
CB A:CYS109 2.8 139.6 1.0
SG A:CYS156 3.0 155.8 1.0
CB A:CYS156 3.2 155.8 1.0
CB A:CYS112 3.8 145.2 1.0
CB A:CYS159 3.9 154.3 1.0
N A:CYS112 4.0 145.2 1.0
CA A:CYS109 4.3 139.6 1.0
ND2 A:ASN163 4.4 150.5 1.0
CA A:CYS112 4.4 145.2 1.0
N A:CYS159 4.6 154.3 1.0
CA A:CYS156 4.7 155.8 1.0
CB A:ALA161 4.8 149.4 1.0
CA A:CYS159 4.8 154.3 1.0
N A:ALA161 4.8 149.4 1.0
N A:GLY160 4.8 153.2 1.0
CB A:THR111 4.8 140.9 1.0
N A:THR111 4.9 140.9 1.0
C A:THR111 5.0 140.9 1.0

Zinc binding site 3 out of 7 in 7aea

Go back to Zinc Binding Sites List in 7aea
Zinc binding site 3 out of 7 in the Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn1201

b:129.0
occ:1.00
 SG B:CYS1092 2.5 118.6 1.0
SG B:CYS1095 2.5 124.1 1.0
SG B:CYS1080 2.5 109.8 1.0
SG B:CYS1083 2.9 111.9 1.0
CB B:CYS1080 3.4 109.8 1.0
CB B:CYS1095 3.4 124.1 1.0
CB B:CYS1092 3.7 118.6 1.0
N B:CYS1095 4.1 124.1 1.0
CB B:CYS1083 4.1 111.9 1.0
CD2 B:TYR1094 4.3 113.1 1.0
N B:CYS1083 4.3 111.9 1.0
CA B:CYS1095 4.4 124.1 1.0
OE1 B:GLN1082 4.5 115.9 1.0
CB B:TYR1094 4.6 113.1 1.0
CB B:GLN1082 4.6 115.9 1.0
CA B:CYS1083 4.8 111.9 1.0
CA B:CYS1080 4.9 109.8 1.0
CG B:TYR1094 5.0 113.1 1.0

Zinc binding site 4 out of 7 in 7aea

Go back to Zinc Binding Sites List in 7aea
Zinc binding site 4 out of 7 in the Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
I:Zn201

b:247.0
occ:1.00
 N I:CYS98 2.8 234.5 1.0
C I:CYS97 2.9 231.8 1.0
CB I:CYS97 2.9 231.8 1.0
N I:ASN99 3.0 239.1 1.0
SG I:CYS97 3.1 231.8 1.0
C I:CYS98 3.1 234.5 1.0
CA I:CYS98 3.3 234.5 1.0
CB I:ASN99 3.3 239.1 1.0
CA I:CYS97 3.4 231.8 1.0
O I:CYS97 3.4 231.8 1.0
SG I:CYS72 3.6 227.3 1.0
CA I:ASN99 3.7 239.1 1.0
O I:CYS98 3.8 234.5 1.0
O I:ARG76 4.0 226.8 1.0
O I:CYS102 4.1 237.3 1.0
SG I:CYS102 4.1 237.3 1.0
CG I:ASN99 4.5 239.1 1.0
CB I:CYS102 4.7 237.3 1.0
N I:CYS97 4.7 231.8 1.0
CB I:CYS98 4.8 234.5 1.0
CB I:CYS72 4.8 227.3 1.0
C I:ASN99 4.9 239.1 1.0
ND2 I:ASN99 4.9 239.1 1.0
C I:CYS102 4.9 237.3 1.0

Zinc binding site 5 out of 7 in 7aea

Go back to Zinc Binding Sites List in 7aea
Zinc binding site 5 out of 7 in the Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
I:Zn202

b:124.5
occ:1.00
 SG I:CYS8 2.5 106.2 1.0
SG I:CYS28 2.5 121.2 1.0
SG I:CYS5 2.5 108.0 1.0
SG I:CYS25 2.6 119.7 1.0
CB I:CYS5 2.7 108.0 1.0
CB I:CYS25 3.0 119.7 1.0
CB I:CYS28 3.8 121.2 1.0
CB I:CYS8 3.9 106.2 1.0
N I:CYS8 4.0 106.2 1.0
CA I:CYS5 4.2 108.0 1.0
CA I:CYS25 4.4 119.7 1.0
CA I:CYS8 4.5 106.2 1.0
N I:CYS28 4.6 121.2 1.0
OG1 I:THR27 4.6 114.5 1.0
N I:GLY9 4.6 103.4 1.0
CB I:TYR30 4.6 117.7 1.0
N I:ASN10 4.7 101.7 1.0
CA I:CYS28 4.7 121.2 1.0
CB I:ASN10 4.8 101.7 1.0
C I:CYS8 4.9 106.2 1.0
C I:CYS5 4.9 108.0 1.0
CD2 I:LEU12 5.0 115.2 1.0
N I:CYS5 5.0 108.0 1.0

Zinc binding site 6 out of 7 in 7aea

Go back to Zinc Binding Sites List in 7aea
Zinc binding site 6 out of 7 in the Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
J:Zn101

b:77.0
occ:1.00
 SG J:CYS7 2.4 56.5 1.0
SG J:CYS45 2.4 59.6 1.0
SG J:CYS10 2.5 57.1 1.0
SG J:CYS44 2.5 57.9 1.0
CB J:CYS7 3.1 56.5 1.0
N J:CYS45 3.3 59.6 1.0
CB J:CYS45 3.6 59.6 1.0
CA J:CYS45 3.6 59.6 1.0
C J:CYS44 3.6 57.9 1.0
CB J:CYS44 3.7 57.9 1.0
CB J:CYS10 3.7 57.1 1.0
N J:CYS10 3.9 57.1 1.0
O J:CYS44 4.1 57.9 1.0
CA J:CYS44 4.3 57.9 1.0
CA J:CYS10 4.3 57.1 1.0
N J:GLY11 4.4 56.1 1.0
NH2 J:ARG42 4.5 58.3 1.0
CA J:CYS7 4.5 56.5 1.0
NE J:ARG42 4.7 58.3 1.0
CB J:THR9 4.8 54.2 1.0
N J:LYS12 4.8 55.1 1.0
CB J:LYS12 4.8 55.1 1.0
C J:CYS7 4.9 56.5 1.0
N J:THR9 4.9 54.2 1.0
C J:CYS10 4.9 57.1 1.0
C J:THR9 4.9 54.2 1.0
N J:CYS44 5.0 57.9 1.0

Zinc binding site 7 out of 7 in 7aea

Go back to Zinc Binding Sites List in 7aea
Zinc binding site 7 out of 7 in the Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 7 of Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
L:Zn101

b:117.6
occ:1.00
 SG L:CYS22 2.5 92.6 1.0
SG L:CYS36 2.5 97.4 1.0
SG L:CYS19 2.5 85.4 1.0
CB L:CYS36 3.0 97.4 1.0
CB L:CYS39 3.1 109.1 1.0
CB L:CYS22 3.5 92.6 1.0
CB L:CYS19 3.7 85.4 1.0
SG L:CYS39 3.7 109.1 1.0
N L:CYS39 3.8 109.1 1.0
CA L:CYS39 3.9 109.1 1.0
N L:CYS22 4.0 92.6 1.0
CB L:TYR41 4.1 88.4 1.0
C L:CYS39 4.3 109.1 1.0
CA L:CYS22 4.4 92.6 1.0
OG1 L:THR24 4.5 92.8 1.0
CA L:CYS36 4.5 97.4 1.0
N L:TYR41 4.5 88.4 1.0
O L:CYS39 4.6 109.1 1.0
O L:TYR41 4.8 88.4 1.0
CA L:TYR41 4.9 88.4 1.0
C L:GLU38 4.9 104.5 1.0
CB L:GLU21 5.0 93.4 1.0

Reference:

M.Girbig, A.D.Misiaszek, M.K.Vorlaender, A.Lafita, H.Groetsch, F.Baudin, A.Bateman, C.W.Mueller. Cryo-Em Structures of Human Rna Polymerase III in Its Unbound and Transcribing States To Be Published.
DOI: 10.1038/S41594-020-00555-5
Page generated: Tue Oct 29 16:46:28 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy