Atomistry » Zinc » PDB 6t5y-6tli » 6t6l
Atomistry »
  Zinc »
    PDB 6t5y-6tli »
      6t6l »

Zinc in PDB 6t6l: Mopeia Virus Exonuclease Domain Complexed Soak with Alendronate

Protein crystallography data

The structure of Mopeia Virus Exonuclease Domain Complexed Soak with Alendronate, PDB code: 6t6l was solved by T.H.V.Nguyen, F.Ferron, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 47.65 / 1.76
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 133.211, 111.337, 49.149, 90, 104.17, 90
R / Rfree (%) 19.1 / 22.2

Other elements in 6t6l:

The structure of Mopeia Virus Exonuclease Domain Complexed Soak with Alendronate also contains other interesting chemical elements:

Manganese (Mn) 3 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Mopeia Virus Exonuclease Domain Complexed Soak with Alendronate (pdb code 6t6l). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Mopeia Virus Exonuclease Domain Complexed Soak with Alendronate, PDB code: 6t6l:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in 6t6l

Go back to Zinc Binding Sites List in 6t6l
Zinc binding site 1 out of 3 in the Mopeia Virus Exonuclease Domain Complexed Soak with Alendronate


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Mopeia Virus Exonuclease Domain Complexed Soak with Alendronate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn602

b:18.9
occ:1.00
OE2 A:GLU400 2.0 17.6 1.0
NE2 A:HIS510 2.1 17.7 1.0
SG A:CYS530 2.3 18.7 1.0
SG A:CYS507 2.3 18.0 1.0
CD A:GLU400 2.9 15.9 1.0
CD2 A:HIS510 2.9 20.4 1.0
CB A:CYS530 3.1 21.8 1.0
OE1 A:GLU400 3.1 16.2 1.0
CE1 A:HIS510 3.2 18.1 1.0
CB A:CYS507 3.3 19.7 1.0
CA A:CYS530 3.7 18.1 1.0
NE2 A:HIS413 3.9 15.8 1.0
CE1 A:HIS413 4.1 17.2 1.0
CG A:HIS510 4.1 18.9 1.0
N A:ALA531 4.2 15.8 1.0
ND1 A:HIS510 4.3 20.1 1.0
CG A:GLU400 4.3 15.2 1.0
C A:CYS530 4.3 17.0 1.0
CE1 A:TYR415 4.4 17.4 1.0
OH A:TYR415 4.7 20.4 1.0
CA A:CYS507 4.7 23.1 1.0
N A:LEU532 4.8 15.4 1.0
CB A:MET509 4.8 22.7 1.0
N A:CYS530 5.0 19.0 1.0

Zinc binding site 2 out of 3 in 6t6l

Go back to Zinc Binding Sites List in 6t6l
Zinc binding site 2 out of 3 in the Mopeia Virus Exonuclease Domain Complexed Soak with Alendronate


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Mopeia Virus Exonuclease Domain Complexed Soak with Alendronate within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn602

b:17.7
occ:1.00
OE1 B:GLU400 2.0 17.4 1.0
NE2 B:HIS510 2.0 13.1 1.0
SG B:CYS530 2.2 15.7 1.0
SG B:CYS507 2.3 18.3 1.0
CD B:GLU400 2.9 14.0 1.0
CD2 B:HIS510 2.9 16.5 1.0
CE1 B:HIS510 3.0 15.9 1.0
CB B:CYS530 3.1 15.6 1.0
OE2 B:GLU400 3.1 17.6 1.0
CB B:CYS507 3.3 16.5 1.0
CA B:CYS530 3.7 16.8 1.0
NE2 B:HIS413 3.9 16.2 1.0
CG B:HIS510 4.1 16.9 1.0
ND1 B:HIS510 4.1 17.0 1.0
CE1 B:HIS413 4.1 20.7 1.0
N B:ALA531 4.2 15.6 1.0
CG B:GLU400 4.3 13.2 1.0
C B:CYS530 4.3 18.1 1.0
CE1 B:TYR415 4.5 16.7 1.0
CA B:CYS507 4.7 21.4 1.0
OH B:TYR415 4.8 20.5 1.0
N B:LEU532 4.8 16.8 1.0
CB B:MET509 4.8 19.9 1.0

Zinc binding site 3 out of 3 in 6t6l

Go back to Zinc Binding Sites List in 6t6l
Zinc binding site 3 out of 3 in the Mopeia Virus Exonuclease Domain Complexed Soak with Alendronate


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Mopeia Virus Exonuclease Domain Complexed Soak with Alendronate within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Zn602

b:19.4
occ:1.00
OE2 C:GLU400 2.0 20.8 1.0
NE2 C:HIS510 2.0 19.2 1.0
SG C:CYS507 2.3 19.5 1.0
SG C:CYS530 2.3 20.0 1.0
CD C:GLU400 2.9 17.2 1.0
CD2 C:HIS510 2.9 20.5 1.0
CE1 C:HIS510 3.1 19.1 1.0
CB C:CYS530 3.1 17.8 1.0
OE1 C:GLU400 3.1 17.6 1.0
CB C:CYS507 3.2 21.0 1.0
CA C:CYS530 3.7 20.3 1.0
NE2 C:HIS413 3.9 17.0 1.0
CG C:HIS510 4.1 18.8 1.0
ND1 C:HIS510 4.1 20.7 1.0
N C:ALA531 4.2 16.4 1.0
CE1 C:HIS413 4.2 20.2 1.0
CG C:GLU400 4.3 18.6 1.0
C C:CYS530 4.3 18.8 1.0
CE1 C:TYR415 4.5 20.0 1.0
CA C:CYS507 4.6 21.6 1.0
OH C:TYR415 4.8 19.9 1.0
N C:LEU532 4.8 17.1 1.0
CB C:MET509 4.9 23.1 1.0
N C:CYS530 5.0 17.8 1.0

Reference:

E.Yekwa, T.H.V.Nguyen, M.Mathieu, I.Imbert, B.Selisko, B.Canard, S.Baize, F.Ferron. Serendipity in Arenaviridae Np Exonuclease Inhibitor Discovery. To Be Published.
Page generated: Tue Oct 29 07:52:02 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy