Zinc in PDB 6mn3: Crystal Structure of Aminoglycoside Acetyltransferase Aac(3)-Iva, Apoenzyme

All present enzymatic activity of Crystal Structure of Aminoglycoside Acetyltransferase Aac(3)-Iva, Apoenzyme:
2.3.1.81;

The structure of Crystal Structure of Aminoglycoside Acetyltransferase Aac(3)-Iva, Apoenzyme, PDB code: 6mn3 was solved by P.J.Stogios, E.Evdokimova, Z.Wawrzak, R.Di Leo, A.Savchenko, A.Joachimiak, K.J.Satchell, Center For Structural Genomics Of Infectious Diseases(Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.77 / 2.40
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	114.170, 55.327, 94.342, 90.00, 102.63, 90.00
R / Rfree (%)	17.6 / 22.2

The structure of Crystal Structure of Aminoglycoside Acetyltransferase Aac(3)-Iva, Apoenzyme also contains other interesting chemical elements:

Chlorine

(Cl)

4 atoms

The binding sites of Zinc atom in the Crystal Structure of Aminoglycoside Acetyltransferase Aac(3)-Iva, Apoenzyme (pdb code 6mn3). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Aminoglycoside Acetyltransferase Aac(3)-Iva, Apoenzyme, PDB code: 6mn3:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Aminoglycoside Acetyltransferase Aac(3)-Iva, Apoenzyme


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Aminoglycoside Acetyltransferase Aac(3)-Iva, Apoenzyme within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn302 b:76.0 occ:1.00 ND1 A:HIS241 2.2 0.1 1.0 SG A:CYS189 2.3 99.8 1.0 SG A:CYS250 2.4 82.2 1.0 SG A:CYS247 2.4 91.6 1.0 CG A:HIS241 3.0 93.7 1.0 CB A:CYS247 3.0 88.6 1.0 CB A:CYS250 3.0 86.7 1.0 CB A:HIS241 3.2 85.6 1.0 CE1 A:HIS241 3.2 96.0 1.0 CB A:CYS189 3.5 0.1 1.0 N A:CYS250 4.0 99.8 1.0 CA A:CYS250 4.1 89.8 1.0 N A:HIS241 4.1 79.4 1.0 CD2 A:HIS241 4.1 97.8 1.0 NE2 A:HIS241 4.2 95.9 1.0 CA A:HIS241 4.3 80.2 1.0 O A:HOH432 4.3 42.2 1.0 N A:CYS189 4.5 97.8 1.0 CA A:CYS247 4.5 96.6 1.0 OE1 A:GLU191 4.5 81.1 1.0 CA A:CYS189 4.6 0.5 1.0 C A:GLU249 4.9 0.1 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Aminoglycoside Acetyltransferase Aac(3)-Iva, Apoenzyme


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Aminoglycoside Acetyltransferase Aac(3)-Iva, Apoenzyme within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn304 b:35.9 occ:1.00 ND1 B:HIS241 2.1 53.6 1.0 SG B:CYS250 2.3 43.0 1.0 SG B:CYS189 2.4 46.3 1.0 SG B:CYS247 2.5 47.5 1.0 CG B:HIS241 3.1 48.7 1.0 CE1 B:HIS241 3.1 49.6 1.0 CB B:CYS247 3.2 43.5 1.0 CB B:HIS241 3.3 39.5 1.0 CB B:CYS189 3.3 43.2 1.0 CB B:CYS250 3.4 41.9 1.0 N B:HIS241 4.1 37.9 1.0 NE2 B:HIS241 4.2 51.0 1.0 CD2 B:HIS241 4.2 50.0 1.0 N B:CYS250 4.2 43.0 1.0 CA B:HIS241 4.3 38.5 1.0 O B:HOH419 4.4 37.3 1.0 N B:CYS189 4.4 47.0 1.0 CA B:CYS250 4.4 41.1 1.0 CA B:CYS189 4.5 41.1 1.0 CA B:CYS247 4.7 49.4 1.0

P.J.Stogios, P.J.Stogios, E.Evdokimova, Z.Wawrzak, R.Di Leo, A.Savchenko, A.Joachimiak, K.J.Satchell, Center For Structural Genomics Of Infectious Diseases(Csgid). N/A N/A.