Zinc in PDB 6c6u: Cryoem Structure of E.Coli Rna Polymerase Elongation Complex Bound with Nusg

Enzymatic activity of Cryoem Structure of E.Coli Rna Polymerase Elongation Complex Bound with Nusg

All present enzymatic activity of Cryoem Structure of E.Coli Rna Polymerase Elongation Complex Bound with Nusg:
2.7.7.6;

Other elements in 6c6u:

The structure of Cryoem Structure of E.Coli Rna Polymerase Elongation Complex Bound with Nusg also contains other interesting chemical elements:

Magnesium (Mg) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Cryoem Structure of E.Coli Rna Polymerase Elongation Complex Bound with Nusg (pdb code 6c6u). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryoem Structure of E.Coli Rna Polymerase Elongation Complex Bound with Nusg, PDB code: 6c6u:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 6c6u

Go back to Zinc Binding Sites List in 6c6u
Zinc binding site 1 out of 2 in the Cryoem Structure of E.Coli Rna Polymerase Elongation Complex Bound with Nusg


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryoem Structure of E.Coli Rna Polymerase Elongation Complex Bound with Nusg within 5.0Å range:
probe atom residue distance (Å) B Occ
J:Zn1501

b:88.7
occ:1.00
SG J:CYS70 2.4 54.5 1.0
SG J:CYS85 2.5 61.5 1.0
SG J:CYS72 2.5 61.9 1.0
CB J:CYS70 3.0 54.5 1.0
CB J:CYS85 3.3 61.5 1.0
CB J:LYS74 3.5 65.9 1.0
N J:LYS74 3.6 65.9 1.0
N J:TYR75 4.0 63.9 1.0
CA J:LYS74 4.0 65.9 1.0
CB J:CYS72 4.1 61.9 1.0
N J:GLY73 4.2 62.5 1.0
CA J:CYS85 4.3 61.5 1.0
CA J:CYS70 4.5 54.5 1.0
N J:CYS72 4.5 61.9 1.0
C J:LYS74 4.5 65.9 1.0
SG J:CYS88 4.6 61.0 1.0
CG J:LYS74 4.6 65.9 1.0
C J:GLY73 4.7 62.5 1.0
CA J:CYS72 4.8 61.9 1.0
CD J:LYS74 4.9 65.9 1.0
CB J:TYR75 4.9 63.9 1.0
CB J:LYS87 4.9 66.3 1.0
N J:LEU71 4.9 53.9 1.0
C J:CYS70 4.9 54.5 1.0
N J:GLU86 5.0 65.1 1.0
C J:CYS72 5.0 61.9 1.0
CG J:TYR75 5.0 63.9 1.0

Zinc binding site 2 out of 2 in 6c6u

Go back to Zinc Binding Sites List in 6c6u
Zinc binding site 2 out of 2 in the Cryoem Structure of E.Coli Rna Polymerase Elongation Complex Bound with Nusg


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryoem Structure of E.Coli Rna Polymerase Elongation Complex Bound with Nusg within 5.0Å range:
probe atom residue distance (Å) B Occ
J:Zn1502

b:50.5
occ:1.00
SG J:CYS888 2.4 40.1 1.0
SG J:CYS814 2.4 44.9 1.0
SG J:CYS898 2.5 36.0 1.0
SG J:CYS895 2.5 35.1 1.0
CB J:CYS814 2.8 44.9 1.0
CB J:CYS888 3.3 40.1 1.0
CB J:CYS898 3.4 36.0 1.0
CA J:CYS888 3.6 40.1 1.0
NH2 J:ARG883 3.6 40.8 1.0
CB J:CYS895 3.8 35.1 1.0
N J:ASP889 3.8 41.7 1.0
CA J:CYS814 4.1 44.9 1.0
C J:CYS888 4.2 40.1 1.0
N J:CYS814 4.3 44.9 1.0
OG1 J:THR816 4.6 52.9 1.0
CA J:CYS898 4.6 36.0 1.0
N J:CYS898 4.6 36.0 1.0
N J:CYS895 4.6 35.1 1.0
OG1 J:THR890 4.6 41.2 1.0
CZ J:ARG883 4.7 40.8 1.0
CA J:CYS895 4.8 35.1 1.0
N J:CYS888 4.8 40.1 1.0
N J:THR890 5.0 41.2 1.0
CA J:ASP889 5.0 41.7 1.0

Reference:

J.Y.Kang, R.A.Mooney, Y.Nedialkov, J.Saba, T.V.Mishanina, I.Artsimovitch, R.Landick, S.A.Darst. Structural Basis For Transcript Elongation Control By Nusg Family Universal Regulators. Cell V. 173 1650 2018.
ISSN: ISSN 1097-4172
PubMed: 29887376
DOI: 10.1016/J.CELL.2018.05.017
Page generated: Wed Dec 16 11:34:26 2020

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