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Atomistry » Zinc » PDB 5fpb-5fvt » 5fpb » |
Zinc in PDB 5fpb: Crystal Structure of Human KDM4D in Complex with 2-1H- Pyrazol-4-Yloxy-3H,4H-Pyrido-3,4-D-Pyrimidin-4-OneProtein crystallography data
The structure of Crystal Structure of Human KDM4D in Complex with 2-1H- Pyrazol-4-Yloxy-3H,4H-Pyrido-3,4-D-Pyrimidin-4-One, PDB code: 5fpb
was solved by
C.Chung,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5fpb:
The structure of Crystal Structure of Human KDM4D in Complex with 2-1H- Pyrazol-4-Yloxy-3H,4H-Pyrido-3,4-D-Pyrimidin-4-One also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Human KDM4D in Complex with 2-1H- Pyrazol-4-Yloxy-3H,4H-Pyrido-3,4-D-Pyrimidin-4-One
(pdb code 5fpb). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human KDM4D in Complex with 2-1H- Pyrazol-4-Yloxy-3H,4H-Pyrido-3,4-D-Pyrimidin-4-One, PDB code: 5fpb: Zinc binding site 1 out of 1 in 5fpbGo back to Zinc Binding Sites List in 5fpb
Zinc binding site 1 out
of 1 in the Crystal Structure of Human KDM4D in Complex with 2-1H- Pyrazol-4-Yloxy-3H,4H-Pyrido-3,4-D-Pyrimidin-4-One
Mono view Stereo pair view
Reference:
S.M.Westaway,
A.G.S.Preston,
M.D.Barker,
F.Brown,
J.A.Brown,
M.Campbell,
C.Chung,
H.Diallo,
C.Douault,
G.Drewes,
R.Eagle,
L.Gordon,
C.Haslam,
T.G.Hayhow,
P.G.Humphreys,
G.Joberty,
R.Katso,
L.Kruidenier,
M.Leveridge,
J.Liddle,
J.Mosley,
M.Muelbaier,
R.Randle,
I.Rioja,
A.Rueger,
G.A.Seal,
R.J.Sheppard,
O.Singh,
J.Taylor,
P.Thomas,
D.Thomson,
D.M.Wilson,
K.Lee,
R.K.Prinjha.
Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-Pyridine Carboxylate Derivatives. J.Med.Chem. V. 59 1357 2016.
Page generated: Sun Oct 27 16:24:45 2024
ISSN: ISSN 0022-2623 PubMed: 26771107 DOI: 10.1021/ACS.JMEDCHEM.5B01537 |
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