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Atomistry » Zinc » PDB 4m2w-4mhq » 4m2w » |
Zinc in PDB 4m2w: Genetically Engineered Carbonic Anhydrase IX in Complex with DorzolamideEnzymatic activity of Genetically Engineered Carbonic Anhydrase IX in Complex with Dorzolamide
All present enzymatic activity of Genetically Engineered Carbonic Anhydrase IX in Complex with Dorzolamide:
4.2.1.1; Protein crystallography data
The structure of Genetically Engineered Carbonic Anhydrase IX in Complex with Dorzolamide, PDB code: 4m2w
was solved by
M.P.Pinard,
C.D.Boone,
B.D.Rife,
C.T.Supuran,
R.Mckenna,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Genetically Engineered Carbonic Anhydrase IX in Complex with Dorzolamide
(pdb code 4m2w). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Genetically Engineered Carbonic Anhydrase IX in Complex with Dorzolamide, PDB code: 4m2w: Zinc binding site 1 out of 1 in 4m2wGo back to Zinc Binding Sites List in 4m2w
Zinc binding site 1 out
of 1 in the Genetically Engineered Carbonic Anhydrase IX in Complex with Dorzolamide
Mono view Stereo pair view
Reference:
M.A.Pinard,
C.D.Boone,
B.D.Rife,
C.T.Supuran,
R.Mckenna.
Structural Study of Interaction Between Brinzolamide and Dorzolamide Inhibition of Human Carbonic Anhydrases. Bioorg.Med.Chem. V. 21 7210 2013.
Page generated: Wed Dec 16 05:34:10 2020
ISSN: ISSN 0968-0896 PubMed: 24090602 DOI: 10.1016/J.BMC.2013.08.033 |
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