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Atomistry » Zinc » PDB 3hqw-3i4c » 3hqw | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 3hqw-3i4c » 3hqw » |
Zinc in PDB 3hqw: Discovery of Novel Inhibitors of PDE10AEnzymatic activity of Discovery of Novel Inhibitors of PDE10AProtein crystallography data
The structure of Discovery of Novel Inhibitors of PDE10A, PDB code: 3hqw
was solved by
J.Pandit,
E.S.Marr,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3hqw:
The structure of Discovery of Novel Inhibitors of PDE10A also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Discovery of Novel Inhibitors of PDE10A
(pdb code 3hqw). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Discovery of Novel Inhibitors of PDE10A, PDB code: 3hqw: Zinc binding site 1 out of 1 in 3hqwGo back to![]() ![]()
Zinc binding site 1 out
of 1 in the Discovery of Novel Inhibitors of PDE10A
![]() Mono view ![]() Stereo pair view
Reference:
P.R.Verhoest,
D.S.Chapin,
M.Corman,
K.Fonseca,
J.F.Harms,
X.Hou,
E.S.Marr,
F.S.Menniti,
F.Nelson,
R.O'connor,
J.Pandit,
C.Proulx-Lafrance,
A.W.Schmidt,
C.J.Schmidt,
J.A.Suiciak,
S.Liras.
Discovery of A Novel Class of Phosphodiesterase 10A Inhibitors and Identification of Clinical Candidate 2-[4-(1-Methyl-4-Pyridin-4-Yl-1H-Pyrazol-3-Yl) -Phenoxymethyl]-Quinoline (Pf-2545920) For the Treatment of Schizophrenia J.Med.Chem. V. 52 5188 2009.
Page generated: Wed Dec 16 04:24:52 2020
ISSN: ISSN 0022-2623 PubMed: 19630403 DOI: 10.1021/JM900521K |
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