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Atomistry » Zinc » PDB 3ciz-3cyu » 3ciz » |
Zinc in PDB 3ciz: Crystal Structure of Hepatitis C Virus Rna-Dependent Rna Polymerase NS5B in Complex with Small Molecule FragmentsEnzymatic activity of Crystal Structure of Hepatitis C Virus Rna-Dependent Rna Polymerase NS5B in Complex with Small Molecule Fragments
All present enzymatic activity of Crystal Structure of Hepatitis C Virus Rna-Dependent Rna Polymerase NS5B in Complex with Small Molecule Fragments:
2.7.7.48; Protein crystallography data
The structure of Crystal Structure of Hepatitis C Virus Rna-Dependent Rna Polymerase NS5B in Complex with Small Molecule Fragments, PDB code: 3ciz
was solved by
J.Hendle,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3ciz:
The structure of Crystal Structure of Hepatitis C Virus Rna-Dependent Rna Polymerase NS5B in Complex with Small Molecule Fragments also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Hepatitis C Virus Rna-Dependent Rna Polymerase NS5B in Complex with Small Molecule Fragments
(pdb code 3ciz). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Hepatitis C Virus Rna-Dependent Rna Polymerase NS5B in Complex with Small Molecule Fragments, PDB code: 3ciz: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 3cizGo back to Zinc Binding Sites List in 3ciz
Zinc binding site 1 out
of 2 in the Crystal Structure of Hepatitis C Virus Rna-Dependent Rna Polymerase NS5B in Complex with Small Molecule Fragments
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 3cizGo back to Zinc Binding Sites List in 3ciz
Zinc binding site 2 out
of 2 in the Crystal Structure of Hepatitis C Virus Rna-Dependent Rna Polymerase NS5B in Complex with Small Molecule Fragments
Mono view Stereo pair view
Reference:
S.S.Antonysamy,
B.Aubol,
J.Blaney,
M.F.Browner,
A.M.Giannetti,
S.F.Harris,
N.Hebert,
J.Hendle,
S.Hopkins,
E.Jefferson,
C.Kissinger,
V.Leveque,
D.Marciano,
E.Mcgee,
I.Najera,
B.Nolan,
M.Tomimoto,
E.Torres,
T.Wright.
Fragment-Based Discovery of Hepatitis C Virus NS5B Rna Polymerase Inhibitors. Bioorg.Med.Chem.Lett. V. 18 2990 2008.
Page generated: Thu Oct 24 11:49:46 2024
ISSN: ISSN 0960-894X PubMed: 18400495 DOI: 10.1016/J.BMCL.2008.03.056 |
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