Zinc in PDB 2vh5: Crystal Structure of Hras(G12V) - Anti-Ras Fv (Disulfide Free Mutant) Complex

The structure of Crystal Structure of Hras(G12V) - Anti-Ras Fv (Disulfide Free Mutant) Complex, PDB code: 2vh5 was solved by T.Tanaka, R.L.Williams, T.H.Rabbitts, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.18 / 2.70
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	75.863, 85.403, 63.084, 90.00, 90.00, 90.00
R / Rfree (%)	21.1 / 29.1

The structure of Crystal Structure of Hras(G12V) - Anti-Ras Fv (Disulfide Free Mutant) Complex also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Zinc atom in the Crystal Structure of Hras(G12V) - Anti-Ras Fv (Disulfide Free Mutant) Complex (pdb code 2vh5). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Crystal Structure of Hras(G12V) - Anti-Ras Fv (Disulfide Free Mutant) Complex, PDB code: 2vh5:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Crystal Structure of Hras(G12V) - Anti-Ras Fv (Disulfide Free Mutant) Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Hras(G12V) - Anti-Ras Fv (Disulfide Free Mutant) Complex within 5.0Å range: probe atom residue distance (Å) B Occ H:Zn1115 b:0.9 occ:1.00 OD1 H:ASP73 2.2 40.4 1.0 OG H:SER75 2.6 38.6 1.0 CG H:ASP73 3.2 40.5 1.0 CB H:SER75 3.5 39.4 1.0 OD2 H:ASP73 3.7 39.4 1.0 N H:SER75 3.8 40.1 1.0 CA H:SER75 4.2 39.7 1.0 N H:ASN74 4.5 40.5 1.0 CB H:ASP73 4.5 40.4 1.0 C H:ASP73 4.6 40.7 1.0 N H:LYS76 4.7 40.0 1.0 CA H:ASP73 4.7 40.4 1.0 C H:SER75 4.8 39.9 1.0 C H:ASN74 5.0 40.3 1.0

Zinc binding site 2 out of 3 in the Crystal Structure of Hras(G12V) - Anti-Ras Fv (Disulfide Free Mutant) Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Hras(G12V) - Anti-Ras Fv (Disulfide Free Mutant) Complex within 5.0Å range: probe atom residue distance (Å) B Occ H:Zn1116 b:84.6 occ:1.00 OD2 H:ASP62 2.1 42.6 1.0 CG H:ASP62 3.0 42.3 1.0 OD1 H:ASP62 3.3 42.6 1.0 CB H:ASP62 4.4 41.6 1.0 O H:HOH2005 4.9 38.2 1.0

Zinc binding site 3 out of 3 in the Crystal Structure of Hras(G12V) - Anti-Ras Fv (Disulfide Free Mutant) Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of Hras(G12V) - Anti-Ras Fv (Disulfide Free Mutant) Complex within 5.0Å range: probe atom residue distance (Å) B Occ R:Zn1169 b:96.3 occ:1.00 O R:HIS166 2.9 41.5 1.0 C R:HIS166 4.1 41.6 1.0 O R:ILE163 4.5 39.6 1.0 O R:ARG164 4.8 40.2 1.0

T.Tanaka, T.H.Rabbitts. Functional Intracellular Antibody Fragments Do Not Require Invariant Intra-Domain Disulfide Bonds. J.Mol.Biol. V. 376 749 2008.
ISSN: ISSN 0022-2836
PubMed: 18187153
DOI: 10.1016/J.JMB.2007.11.085