Zinc in PDB 2drp: The Crystal Structure of A Two Zinc-Finger Peptide Reveals An Extension to the Rules For Zinc-Finger/Dna Recognition

The structure of The Crystal Structure of A Two Zinc-Finger Peptide Reveals An Extension to the Rules For Zinc-Finger/Dna Recognition, PDB code: 2drp was solved by L.Fairall, J.W.R.Schwabe, L.Chapman, J.T.Finch, D.Rhodes, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	6.00 / 2.80
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	60.700, 64.600, 117.600, 90.00, 90.00, 90.00
R / Rfree (%)	19.3 / n/a

The binding sites of Zinc atom in the The Crystal Structure of A Two Zinc-Finger Peptide Reveals An Extension to the Rules For Zinc-Finger/Dna Recognition (pdb code 2drp). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the The Crystal Structure of A Two Zinc-Finger Peptide Reveals An Extension to the Rules For Zinc-Finger/Dna Recognition, PDB code: 2drp:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the The Crystal Structure of A Two Zinc-Finger Peptide Reveals An Extension to the Rules For Zinc-Finger/Dna Recognition


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The Crystal Structure of A Two Zinc-Finger Peptide Reveals An Extension to the Rules For Zinc-Finger/Dna Recognition within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn171 b:27.1 occ:1.00 NE2 A:HIS134 2.0 25.1 1.0 NE2 A:HIS129 2.0 20.6 1.0 SG A:CYS116 2.3 30.6 1.0 SG A:CYS113 2.3 27.6 1.0 CD2 A:HIS134 2.9 30.4 1.0 CE1 A:HIS129 2.9 22.1 1.0 CE1 A:HIS134 3.0 30.8 1.0 CD2 A:HIS129 3.1 23.4 1.0 CB A:CYS113 3.3 23.6 1.0 CB A:CYS116 3.4 26.6 1.0 N A:CYS116 3.7 29.4 1.0 CA A:CYS116 4.1 26.2 1.0 CG A:HIS134 4.1 30.0 1.0 ND1 A:HIS129 4.1 22.8 1.0 ND1 A:HIS134 4.1 32.0 1.0 CG A:HIS129 4.2 18.6 1.0 CB A:VAL115 4.4 23.7 1.0 C A:VAL115 4.7 30.7 1.0 C A:CYS116 4.7 29.0 1.0 CA A:CYS113 4.7 22.9 1.0 CB A:ARG118 4.7 27.4 1.0 CD A:ARG118 4.8 41.3 1.0 O A:CYS113 4.9 34.3 1.0 CA A:VAL115 4.9 26.7 1.0 C A:CYS113 5.0 28.1 1.0 CG1 A:VAL115 5.0 11.5 1.0

Zinc binding site 2 out of 4 in the The Crystal Structure of A Two Zinc-Finger Peptide Reveals An Extension to the Rules For Zinc-Finger/Dna Recognition


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of The Crystal Structure of A Two Zinc-Finger Peptide Reveals An Extension to the Rules For Zinc-Finger/Dna Recognition within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn172 b:36.2 occ:1.00 NE2 A:HIS164 2.0 31.5 1.0 NE2 A:HIS159 2.0 39.5 1.0 SG A:CYS146 2.3 30.8 1.0 SG A:CYS143 2.3 33.4 1.0 CD2 A:HIS164 3.0 30.5 1.0 CD2 A:HIS159 3.0 36.7 1.0 CE1 A:HIS159 3.0 34.0 1.0 CE1 A:HIS164 3.1 35.1 1.0 CB A:CYS143 3.2 28.8 1.0 CB A:CYS146 3.4 43.1 1.0 N A:CYS146 3.7 38.8 1.0 CA A:CYS146 4.1 38.4 1.0 CG A:HIS164 4.1 32.4 1.0 ND1 A:HIS159 4.2 36.5 1.0 ND1 A:HIS164 4.2 35.9 1.0 CG A:HIS159 4.2 34.6 1.0 CB A:PHE145 4.6 37.1 1.0 CG2 A:ILE163 4.6 35.0 1.0 CA A:CYS143 4.6 32.6 1.0 C A:CYS146 4.8 38.7 1.0 N A:PHE147 4.8 40.1 1.0 C A:PHE145 4.8 44.0 1.0 CG2 A:VAL160 4.9 35.1 1.0 CD2 A:PHE145 4.9 41.2 1.0

Zinc binding site 3 out of 4 in the The Crystal Structure of A Two Zinc-Finger Peptide Reveals An Extension to the Rules For Zinc-Finger/Dna Recognition


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of The Crystal Structure of A Two Zinc-Finger Peptide Reveals An Extension to the Rules For Zinc-Finger/Dna Recognition within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn173 b:39.7 occ:1.00 NE2 D:HIS129 2.0 32.8 1.0 NE2 D:HIS134 2.0 51.9 1.0 SG D:CYS113 2.2 37.2 1.0 SG D:CYS116 2.3 39.3 1.0 CE1 D:HIS129 2.9 24.1 1.0 CD2 D:HIS134 3.0 48.3 1.0 CD2 D:HIS129 3.0 27.2 1.0 CE1 D:HIS134 3.0 55.2 1.0 CB D:CYS113 3.2 48.4 1.0 CB D:CYS116 3.3 42.8 1.0 N D:CYS116 3.7 41.7 1.0 CA D:CYS116 4.0 42.4 1.0 ND1 D:HIS129 4.1 30.6 1.0 CG D:HIS134 4.1 51.3 1.0 CG D:HIS129 4.1 31.4 1.0 ND1 D:HIS134 4.2 55.5 1.0 CB D:VAL115 4.5 41.6 1.0 C D:CYS116 4.6 45.6 1.0 CA D:CYS113 4.6 44.8 1.0 CB D:ARG118 4.7 51.3 1.0 OG D:SER133 4.7 49.6 1.0 CD D:ARG118 4.7 74.2 1.0 C D:VAL115 4.7 40.8 1.0 CG D:ARG118 4.8 61.1 1.0 N D:SER117 4.8 44.0 1.0 OH D:TYR120 4.8 16.1 1.0 N D:ARG118 4.9 43.6 1.0 O D:CYS113 4.9 46.0 1.0 CG1 D:VAL115 5.0 37.3 1.0

Zinc binding site 4 out of 4 in the The Crystal Structure of A Two Zinc-Finger Peptide Reveals An Extension to the Rules For Zinc-Finger/Dna Recognition


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of The Crystal Structure of A Two Zinc-Finger Peptide Reveals An Extension to the Rules For Zinc-Finger/Dna Recognition within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn174 b:36.0 occ:1.00 NE2 D:HIS164 2.0 33.2 1.0 NE2 D:HIS159 2.0 39.8 1.0 SG D:CYS143 2.3 41.6 1.0 SG D:CYS146 2.3 34.7 1.0 CD2 D:HIS164 2.9 33.7 1.0 CD2 D:HIS159 3.0 33.0 1.0 CE1 D:HIS164 3.0 40.0 1.0 CE1 D:HIS159 3.1 35.7 1.0 CB D:CYS143 3.2 33.9 1.0 CB D:CYS146 3.4 40.0 1.0 N D:CYS146 3.9 38.8 1.0 CG D:HIS164 4.1 35.0 1.0 ND1 D:HIS164 4.1 39.8 1.0 C D:PHE145 4.2 35.1 1.0 CG D:HIS159 4.2 30.2 1.0 ND1 D:HIS159 4.2 33.3 1.0 CA D:CYS146 4.2 39.9 1.0 CB D:PHE145 4.4 37.6 1.0 O D:PHE145 4.5 42.5 1.0 CA D:CYS143 4.6 37.5 1.0 CA D:PHE145 4.6 32.6 1.0 N D:PHE145 4.7 36.1 1.0 C D:CYS146 4.8 42.8 1.0 CG2 D:ILE163 4.9 34.1 1.0 CG2 D:VAL160 4.9 25.2 1.0 C D:CYS143 4.9 38.9 1.0 O D:CYS143 4.9 42.6 1.0

L.Fairall, J.W.Schwabe, L.Chapman, J.T.Finch, D.Rhodes. The Crystal Structure of A Two Zinc-Finger Peptide Reveals An Extension to the Rules For Zinc-Finger/Dna Recognition. Nature V. 366 483 1993.
ISSN: ISSN 0028-0836
PubMed: 8247159
DOI: 10.1038/366483A0