Zinc in PDB 9qwn: Human UPF1 in Complex with the Histone Stem Loop Rna

All present enzymatic activity of Human UPF1 in Complex with the Histone Stem Loop Rna:
3.6.4.12; 3.6.4.13;

The binding sites of Zinc atom in the Human UPF1 in Complex with the Histone Stem Loop Rna (pdb code 9qwn). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Human UPF1 in Complex with the Histone Stem Loop Rna, PDB code: 9qwn:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Human UPF1 in Complex with the Histone Stem Loop Rna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Human UPF1 in Complex with the Histone Stem Loop Rna within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:304.9 occ:1.00 SG A:CYS213 2.3 272.3 1.0 SG A:CYS209 2.3 229.3 1.0 SG A:CYS186 2.3 239.2 1.0 SG A:CYS183 2.3 223.4 1.0 CB A:CYS209 2.5 229.3 1.0 CB A:CYS183 2.8 223.4 1.0 CB A:CYS213 3.5 272.3 1.0 CB A:CYS186 3.5 239.2 1.0 CA A:CYS209 3.7 229.3 1.0 N A:CYS209 3.7 229.3 1.0 N A:CYS186 3.8 239.2 1.0 CA A:CYS186 4.2 239.2 1.0 CA A:CYS183 4.3 223.4 1.0 N A:GLY187 4.4 224.1 1.0 CB A:CYS188 4.4 200.0 1.0 N A:CYS188 4.5 200.0 1.0 C A:CYS186 4.7 239.2 1.0 CB A:ASN185 4.7 233.5 1.0 C A:CYS209 4.8 229.3 1.0 CA A:CYS213 4.9 272.3 1.0 C A:LEU208 4.9 211.0 1.0 C A:ASN185 4.9 233.5 1.0 C A:CYS183 5.0 223.4 1.0

Zinc binding site 2 out of 3 in the Human UPF1 in Complex with the Histone Stem Loop Rna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Human UPF1 in Complex with the Histone Stem Loop Rna within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1002 b:246.0 occ:1.00 ND1 A:HIS155 2.1 191.7 1.0 SG A:CYS145 2.3 200.8 1.0 SG A:CYS123 2.3 207.6 1.0 SG A:CYS126 2.3 210.2 1.0 CE1 A:HIS155 2.7 191.7 1.0 CB A:CYS123 3.1 207.6 1.0 CB A:CYS126 3.2 210.2 1.0 CG A:HIS155 3.3 191.7 1.0 CB A:CYS145 3.4 200.8 1.0 N A:CYS126 3.4 210.2 1.0 CA A:CYS126 3.9 210.2 1.0 CB A:HIS155 3.9 191.7 1.0 NE2 A:HIS155 3.9 191.7 1.0 CB A:TYR125 4.1 201.1 1.0 N A:CYS145 4.1 200.8 1.0 CD2 A:HIS155 4.2 191.7 1.0 CA A:CYS145 4.3 200.8 1.0 N A:GLY127 4.3 214.8 1.0 C A:TYR125 4.4 201.1 1.0 C A:CYS126 4.6 210.2 1.0 CA A:CYS123 4.6 207.6 1.0 CA A:TYR125 4.6 201.1 1.0 N A:TYR125 4.7 201.1 1.0 N A:ILE128 4.9 213.7 1.0 CD2 A:TYR125 5.0 201.1 1.0 C A:CYS145 5.0 200.8 1.0

Zinc binding site 3 out of 3 in the Human UPF1 in Complex with the Histone Stem Loop Rna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Human UPF1 in Complex with the Histone Stem Loop Rna within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1003 b:302.5 occ:1.00 OG A:SER140 2.0 207.4 1.0 SG A:CYS137 2.3 212.1 1.0 NE2 A:HIS159 2.3 195.5 1.0 SG A:CYS165 2.3 209.3 1.0 CB A:SER140 2.7 207.4 1.0 CE1 A:HIS159 3.0 195.5 1.0 N A:SER140 3.2 207.4 1.0 CB A:CYS165 3.3 209.3 1.0 CD2 A:HIS159 3.4 195.5 1.0 CB A:CYS137 3.4 212.1 1.0 CA A:SER140 3.5 207.4 1.0 CB A:THR139 4.0 204.8 1.0 C A:THR139 4.1 204.8 1.0 ND1 A:HIS159 4.2 195.5 1.0 CG A:HIS159 4.4 195.5 1.0 CA A:THR139 4.5 204.8 1.0 CB A:ALA163 4.5 202.3 1.0 OG1 A:THR139 4.6 204.8 1.0 N A:THR139 4.6 204.8 1.0 C A:SER140 4.7 207.4 1.0 CA A:CYS165 4.7 209.3 1.0 CA A:CYS137 4.8 212.1 1.0 CG2 A:THR139 4.9 204.8 1.0

A.Machado De Amorim, B.Loll, T.Hilal, S.Chakrabarti. Human UPF1 in Complex with the Histone Stem Loop Rna To Be Published.